cognitive impairment may be a common even at the onset of multiple sclerosis (ms). in this case-control study, we tried to find out the probable relationship between homocysteine levels and cerebral atrophy or cognitive impairment in patients with multiple sclerosis. one hundred fifty six patients who had ms according to mcdonald diagnostic criteria were included in this study. patients’ age, g...

An efficient brain segmentation technique of magnetic resonance image (MRI) is proposed for the sake of atrophy detection. Early detection of brain atrophy indicates many neurodiseases. The paper also proposes a new simple assessment for brain atrophy as an atrophy ratio measure. Experiments on cognitive normal and atrophied MRI Brain images demonstrate the promising segmentation results of the...

This scientific commentary refers to ‘Identification of multiple system atrophy mimicking Parkinson’s disease or progressive supranuclear palsy’ by Miki et al. (doi:10.1093/brain/awab017).

The association between cerebrospinal fluid (CSF) amyloid beta (A?) A?38 or A?40 and brain grey- white matter integrity is poorly understood. We studied this in 213 cognitively normal 70-year-olds, subgroups defined by presence/absence of the APOE ?4 allele A? pathology: A??/APOE?, A?+/APOE?, A??/APOE+ A?+/APOE+. CSF was quantified using ELISA genotyping for performed. Low A?42 plaque pathology...

Introduction: An organic disorder is defined as psychiatric syndromes, the fundamental manifestations of which are direct consequence a known anatomophysiological alteration brain. HIV neurotropic virus, infects central nervous system early. Despite widely high prevalence HIV-related brain atrophy, presence psychotic symptoms rare. Case report: This 28-year-old patient with recent diagnosis Wes...

OBJECTIVE To characterize whole-brain atrophy in relapsing-remitting MS (RRMS) patients over an 8-year period. The specific goals of this study were to determine if brain atrophy is related to subsequent disability status and to identify MRI correlates of atrophy progression. METHODS A follow-up study was conducted to reassess patients from a phase III trial of interferon beta-1a (IFNbeta-1a)...

Dyke-Davidoff-Masson Syndrome (DDMS) is a rare neurological condition characterised clinically by recurrent seizures, facial asymmetry, hemiplegia and mental retardation likely due to foetal or early childhood cerebral insult. We describe the MRI findings of DDMS in 10-year-old male child. brain revealed right atrophy, ipsilateral thickening calvarium, lateral ventricular dilatation, hyper-pneu...