background bloodstream infection (bsi) is an important cause of mortality and morbidity and among the most common health-care associated infections. in this study we described the frequency of occurrence and antimicrobial susceptibility patterns of nosocomial and community-acquired bsi isolates from a teaching hospital in tehran, iran. patients and methods this cross-sectional study was conduct...

Critically ill patients with acute renal failure (ARF) treated with renal replacement therapy (RRT) have a high mortality. The authors evaluated a cohort of 704 consecutive intensive care unit (ICU) patients with ARF treated with RRT to determine whether there was an increased incidence of nosocomial bloodstream infection and whether this resulted in a worse outcome. The incidence of nosocomial...

OBJECTIVE To investigate the pathogenesis of bloodstream infection by Staphylococcus epidermidis, using the molecular epidemiology, in high-risk neonates. METHODS We conducted a prospective study of a cohort of neonates with bloodstream infection using central venous catheters for more than 24h. "National Healthcare Safety Network" surveillance was conducted. Genotyping was performed by DNA f...

background and objectives: nicu acquired infections are associated with increased mortality rates, prolonged duration of hospitalization in survivors and increased cost of neonatal health care. the frequency of these infections has increased in recent decades as a result of   increased survival of low birth weight infants. in this study,  incidence of nosocomial blood stream infection and risk ...

OBJECTIVE Catheter-related bloodstream infections are associated with significant costs and adverse consequences. Arterial catheters are commonly used in the critical care setting and are among the most heavily manipulated vascular access devices. We sought to evaluate the prevalence of arterial catheter-related bloodstream infection. DATA SOURCES PubMed, CinAHL, EMBASE, and Web of Science. ...

BACKGROUND The clinical course of Staphylococcus aureus bloodstream infection is unpredictable and bacterial virulence, host immune response and patient characteristics are among the factors that contribute to the clinical course of infection. To investigate the relationship between cytokine response and clinical outcome, circulating cytokine levels were investigated in response to S. aureus bl...

AIMS The epidemiological assessment of cases of coagulase negative staphylococcal catheter related bloodstream infection. METHODS Two hundred and thirty patients with suspected catheter related bloodstream infection were evaluated over a two year period. Central venous catheters were cultured both endoluminally and extraluminally. Peripheral blood, catheter hubs, skin entry, and skin control ...

BACKGROUND Bloodstream infection is a common cause of hospitalization, morbidity and death in children. The impact of antimicrobial resistance and HIV infection on outcome is not firmly established. METHODS We assessed the incidence of bloodstream infection and risk factors for fatal outcome in a prospective cohort study of 1828 consecutive admissions of children aged zero to seven years with...