background: long surgery causes hypothermia and increased bleeding and can increase the arterial blood lactate levels during anesthesia. it causes cellular hypoxia and its complications. considering the core temperature of the patient during surgery it can prevent hypoxia. this study aimed to compare the effects of different temperatures on the core temperature and the concentrations of lactate...

conclusions comparing the serum lactate level before operation and 24 hours after the operation showed that the number of received blood units had a significant effect on serum lactate. we found no significant effect for blood storage duration; however, the number of given blood units was more significant. patients and methods in a cross-sectional study, 228 patients referred to three hospitals...

Minimally invasive techniques to access subcutaneous adipose tissue for glucose monitoring are successfully applied in type1 diabetic and critically ill patients. During critical illness, the addition of a lactate sensor might enhance prognosis and early intervention. Our objective was to evaluate SAT as a site for lactate measurement in critically ill patients. In 40 patients after major cardi...

Lactate in the Cerebrospinal Fluid and Pressure-Flow Relationships in Canine Cerebral Circulation • In 11 dogs, lactate and pH in the cerebrospinal fluid and in the arterial and the venous blood were measured during stepwise reductions of the arterial blood pressure by controlled bleeding. Increase in lactate and decrease in pH of the cerebrospinal fluid occurred with lowering of the mean arter...

BACKGROUND Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care unit, and to compare how capillary and arterial lactate trend over time in patients undergoing resuscitat...

Objective: To examine the relationship between newborn umbilical cord blood lactate and pH levels, mode of delivery and short-term neonatal outcome. Materials and methods: Umbilical cord arterial and venous lactate and pH values, mode of delivery, birth weight, gestational age, Apgar scores were extracted from the Obstetrix database at Nepean Hospital in Sydney. More than 7400 newborn cord bloo...

We describe the isotopic exchange of lactate and pyruvate after arm vein infusion of [3-(13)C]lactate in men during rest and exercise. We tested the hypothesis that working muscle (limb net lactate and pyruvate exchange) is the source of the elevated systemic lactate-to-pyruvate concentration ratio (L/P) during exercise. We also hypothesized that the isotopic equilibration between lactate and p...

Lactic acidosis is a clinical condition due to accumulation of H(+) ions from lactic acid, characterized by blood lactate levels >5 mM and arterial pH <7.25. In addition to supportive care, treatment usually consists of intravenous NaHCO(3), with a resultant mortality >60%. Dichloroacetate (DCA) is a compound that lowers blood lactate levels under various conditions in both man and laboratory a...