objectives : platelet preparations are commonly used to enhance bone and soft tissue regeneration. considering the existing controversies on the efficacy of platelet products for tissue regeneration, more in vitro studies are required. the aim of the present study was to compare the in vitro effects of plasma rich in growth factors (prgf) and platelet-rich fibrin (prf) on proliferation and viab...

objective: menstrual blood stromal stem cells (mbscs) share some phenotypic and functional similarities with mesenchymal stem cells (mscs). mscs are shown to inhibit either the function or generation of different immune cells, including dendritic cells (dcs). however, data regarding mbscs’ potential effects on immune system cells are elusive. here, we examine whether mbscs affect the generation...

background: blood is permanently exposed to oxidation stress and therefore has a high antioxidants capacity. many different factors increasing the demand for the antioxidant capacity can be observed in the stored blood of donors. consequently, damage to erythrocytes by free radicals may occur. so it is useful to control the alternation of anti-oxidant enzymes in stored blood at different days o...

a simple inexpensive con!nuous quality control method, by means of eight basic blood coun!ng parameters, obtained from automated hematology analyzers, using pa!ent samples, is described. a few samples with low, normal and high values were selected and introduced to the instrument early in the morning as the first count, the results of which are plo#ed on the appropriate chart as dots. the same ...

background: brain hypoxia-ischemia is a human neonatal injury that is considered a candidate for stem cell therapy. methods: the possible therapeutic potential of human umbilical cord blood (hucb) stem cells was evaluated in 14-day-old rats subjected to the right common carotid occlusion, a model of neonatal brain hypoxia-ischemia. seven days after hypoxia-ischemia, rats received either saline ...

conclusions when evaluating flank pain in patients, it is important to remember that cbc parameters may support urinary stone disease, and considering cbc results may be useful in the diagnosis of urinary stone disease. patients and methods this study was a retrospective observational study of 3,099 patients who were admitted to the urology outpatient clinic or diagnosed with urinary stone dise...

conclusions our results suggested that cb-nk cells progenitors could proliferate and differentiate on feeder layer of amnion membrane mscs in combination with specific cytokines to produce nk cells for immunotherapy. results combination of cytokines and msc layer yielded significant fold expansion in comparison with cytokines without feeder conditions (day 7: 5.2 ± 1.12 and 2 ± 0.78, respective...

background: red blood cell and other blood products play a crucial role in management of different disease processes, but in spite of implementation of crucial steps to improve the process of request for blood and blood consumption, there is still not enough information available regarding the proper practice in many medical centres. we aimed to evaluate the status of blood product requests and...

blood brain barrier (bbb) is a specialized non fenestrate barrier that formation by the endothelial cells and controls the transportation of the cells and molecules in to the brain. reducing in function of bbb is one of disruptions in neurological diseases like multiple sclerosis. endothelial progenitor cell (epc) help to the bbb to control the diapedesis of inflammatory cells & molecules in to...

introduction: neuroblastoma is the most common extracranial solid tumor in children, accounting for 8% to 10% of all childhood cancers. significantly, autologous transplantation appeared to have the largest impact on survival for the high risk subset of patients, such as those with n-myc amplified metastatic disease diagnosed after age 2 years. patients and methods: this study includes high ris...