infantile haemangiomas (ih) are the most common vascular tumors occurring in early childhood, with a prevalence of approximately 5-10% of infants. these vascular tumors are divided into two main groups including infantile haemangioma and vascular malformations. although, haemangioma of infancy are common, benign and self-limited tumors, a significant percent of these lesions are associated with...

there are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. in this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. l...

Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors. Calcium channel blockers belong to cardiovascular medicine and administrated to treatment of hypertension, angina and cardiac arrhythmia because of vasodilatory...

chronic anal fissure is the most common cause of anal pain associated with internal anal sphincter hypertonia. reduction of hypertonocity is a special treatment for fissure healing. for this purpose chronic anal fissures were conventionally treated by anal dilatation or by lateral sphincterotomy. however, both of these methods may cause a degree of incontinence in some patients. the uptake of m...

introduction: omperazole as a very useful drug in peptic ulcer which needs to be converted to active form and its activation requires acidic enviornments. h2 blockers and antacids can prevent this activation by elevation of ph in the gastrointestinal system thus diminishing omperazole effectiveness. in this study, cases of coadministration of omperazsole with h2 blockers and antiacids has been ...

Background and Aim: High blood pressure is a common cardiovascular disease. Most cardiovascular medications have adverse oral side effects. This study aimed to determine the prevalence of oral manifestations associated with the intake of anti-hypertensive medications. Materials and Methods: This cross-sectional analytical study examined 142 patients with a history of hypertension referred to D...

the high performance liquid chromatography (hplc) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (dea) as the mobile phase and related chiral recognition mechanisms were discussed. enantiomeric separation of the fourβ-blockers was ...

Entorhinal cortex (EC) is one of the first Entorhinal cortex (EC) is one of the first cerebral regions affected in Alzheimer’sdisease (AD). The pathology propagates to neighboring cerebral regions through a prion-likemechanism. In AD, intracellular calcium dyshomeostasis is associated with endoplasmicreticulum (ER) stress. This study was designed to examine hippocampal ER stre...