BACKGROUND Publications on the use of the bispectral index for sedation monitoring in the intensive care unit are increasing. However, few studies have involved correlation of bispectral index with serum drug concentrations. OBJECTIVES To assess the degree of correlation between bispectral index values, scores on the Sedation-Agitation Scale, and steady-state serum concentrations of lorazepam...

BACKGROUND AND OBJECTIVE The reliability of the Bispectral Index for evaluating and monitoring the depth of general anaesthesia in children is not as great as for that in adults. Therefore we analysed Bispectral Index performance in children by comparing changes in Bispectral Index values during a standardized and equipotent anaesthetic regimen using either halothane or sevoflurane for the indu...

EDITOR: Several authors have reported sudden increases of the bispectral index values during different procedures such as endoscopic shoulder surgery [1], deep hypothermic circulatory arrest [2] or after using an upper-body blanket for warming [3]. In addition, spurious bispectral index values can be observed when the electromyogram activity of the bispectral index monitor reaches a value of 50...

Background: The use of clinical signs may not be reliable to measure the hypnotic component of anaesthesia. Bispectral Index monitoring provides a direct measurement of the hypnotic effect of the anaesthetic agent used and it may have certain clinical advantages over clinical signs. Objective: This study consists of dose requirement of propofol with bispectral Index monitoring and without bispe...

We report that intraoperative NIM-2 monitoring devices can interfere with bispectral index monitoring. A 45-year-old male with chronic otits media underwent tympanolasty under general anesthesia with NIM-2 monitoring and bispectral index monitoring at our institution. And then, bispectral index monitoring was severely interrupted by facial nerve monitoring.

THE bispectral index (BIS, Aspect Medical Systems, Framingham, MA) is a complex electroencephalographic (EEG) parameter that integrates several disparate descriptors of the EEG into a single variable and correlates behavioral assessments of sedation and hypnosis. We report two cases in which the bispectral index failed to measure depth of anesthesia but instead was a measure of electromyographi...

Background: Inadequate depth of anesthesia leads to release of stress hormones. Electroencephalographic monitoring by bispectral index is a guide to asses the depth of anesthesia. The aim of the present study was to measure the serum cortisol levels as an index of stress response in patients who are candidates for coronary artery bypass graft surgery in two groups of patients. Methods: Seventy-...