CONTEXT Major depressive disorder, the most common psychiatric illness, is often chronic and a major cause of disability. Many patients with major depressive episodes who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do not include mood stabilizers. OBJECTIVE To determine the frequency of bipolar disorder symptoms in patien...

bipolar spectrum disorders may often go undiagnosed or unrecognized. the aim of this study was to determine the proportion of bipolar disorder symptoms in iranian patients with a major depressive episode.313 patients with a current dsm-iv-tr (diagnostic and statistical manual of mental disorders 4th ed. text rev.) diagnosed with a major depressive episode entered this cross-sectional study. thi...

OBJECTIVE Bipolar spectrum disorders may often go undiagnosed or unrecognized. The aim of this study was to determine the proportion of bipolar disorder symptoms in Iranian patients with a major depressive episode. METHODS 313 patients with a current DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders 4th ed. Text rev.) diagnosed with a major depressive episode entered this cross...

declarator, 181, 1190access-specifier, 231, 1192additive-expression, 118, 1183alias-declaration, 139, 1186alignment-specifier, 175, 1189and-expression, 122, 1183asm-definition, 171, 1188assignment-expression, 125, 1184assignment-operator, 125, 1184attribute, 175, 1189attribute-argument-clause, 175, 1189attribute-declaration, 139, 1186attribute-lis...

BACKGROUND This cross-sectional study sought to identify factors associated with antenatal depression in pregnant Korean females, including sociodemographic parameters, social support, social conflict, and bipolarity. METHODS Eighty-four pregnant women were recruited to complete questionnaires on sociodemographic factors, obstetric history, depressive symptoms, and bipolarity. Depressive symp...

BACKGROUND 'With Significant Callous-Unemotional Traits' has been proposed as a specifier for conduct disorder (CD) in the upcoming revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). The impact of this specifier on children diagnosed with CD should be considered. METHODS A multi-site cross-sectional design with volunteers (n = 1136) in the third-seventh grades and ...

In recent years, there has been an increasing interest in handling (heterogeneous) bipolarity in order to deal more adequately with user preferences in information management. Different approaches have been presented. With respect to criteria specification in either flexible database querying or decision support, a main distinction can be made between bipolarity that is specified inside a singl...

Gram-positive bacteria utilize a tRNA-responsive transcription antitermination mechanism, designated the T box system, to regulate expression of many amino acid biosynthetic and aminoacyl-tRNA synthetase genes. The RNA transcripts of genes controlled by this mechanism contain 5' untranslated regions, or leader RNAs, that specifically bind cognate tRNA molecules through pairing of nucleotides in...

Although the microtubule-depolymerizing KinI motor Kif2a is abundantly expressed in neuronal cells, we now show it localizes to centrosomes and spindle poles during mitosis in cultured cells. RNAi-induced knockdown of Kif2a expression inhibited cell cycle progression because cells assembled monopolar spindles. Bipolar spindle assembly was restored in cells lacking Kif2a by treatments that alter...