background : lack of insight in patients with bipolar i disorder has been associated with poor course and clinical outcome and compromised therapeutic compliance. therefore, it is important to evaluate insight and use more specialized scales such as mood disorder insight scale (mdis) in these patients. our objective in this study was to assess validity and reliability of persian version of mdis...

bipolar spectrum disorders may often go undiagnosed or unrecognized. the aim of this study was to determine the proportion of bipolar disorder symptoms in iranian patients with a major depressive episode.313 patients with a current dsm-iv-tr (diagnostic and statistical manual of mental disorders 4th ed. text rev.) diagnosed with a major depressive episode entered this cross-sectional study. thi...

objective: several studies show co morbidity of anxiety disorders amongst patients with bipolar and unipolar disorders. it is associated with an intensification of symptoms, insufficient treatment response, non recovery, poor functional outcome and suicidality. the aim of this study was to show the frequency of anxiety disorders comorbidity and the relationship between comorbidity and suicide a...

conclusions the obtained results confirm some previous studies regardinga gender specific association of maoa gene with the bipolar disorder. results significant associations were observed regarding maoa-ca (p = 0.016) and maoa-vntr (p = 0.004) polymorphisms in the bipolar females. there was no association between maoa-rflp and bipolar disorder. patients and methods this study is a case-control...

objective: patients with bipolar mood disorder constitute a relatively large number of individuals hospitalized in psychiatric hospitals. this disorder is highly co-morbid with other psychiatric disorders and may effect their clinical course. the goal of this study was to determine the co-occurrence rate of anxiety disorders and substance abuse with bipolar mood disorders and their impact on cl...

background : the existing evidence about the clinical situations of the bipolar patients with opioid dependence is scarce. the present study was carried out to compare the clinical features and course of the bipolar disorder type i regarding the two subgroups of opioid dependent and non-dependent. methods : there were 178 adult patients with bipolar disorder type i consecutively referred to the...

Background and Purpose: Patients with Bipolar I Disorder recurrence experiences mood variation between manic and depression during the time. Hence, that is need to the longitudinal study on Bipolar Disorder patients. This study aims to evaluate the effective factors on Bipolar I Disorder frequent recurrence in 5 years longitudinal study using generalized estimation equations (GEE) m...

introduction: substance abuse/dependency is one of the most important comorbidity in bipolar patients. therefore, recognizing the patterns of substance use is valuable in treatment and management of patients. this study was conducted to determine patterns of substance abuse among bipolar patients who were hospitalized in an educational hospital. methods : this was a descriptive-analytical study...