with Cell Immuno-Chip, Yuzhi Yang, Chunxiu Zhang, Zuming Tang, Xiaomin Zhang, and Zuhong Lu ( National Laboratory for Molecular and Biomolecular Electronics and 2 Department of Materials Science and Engineering, Southeast University, Nanjing, Peoples Republic of China; 3 The Hospital of Southeast University, Nanjing, Peoples Republic of China; * address correspondence to this author at: Nationa...

EDITORIAL article Front. Bioeng. Biotechnol., 08 August 2023Sec. Biosensors and Biomolecular Electronics Volume 11 - 2023 | https://doi.org/10.3389/fbioe.2023.1264337

Self-assembly of biological molecules on solid materials is central to the "bottom-up" approach to directly integrate biology with electronics. Inspired by biology, exquisite biomolecular nanoarchitectures have been formed on solid surfaces. We demonstrate that a combinatorially-selected dodecapeptide and its variants self-assemble into peptide nanowires on two-dimensional nanosheets, single-la...

Charge transport at the molecular scale builds the cornerstone of molecular electronics (ME), a novel paradigm aiming at the realization of nanoscale electronics via tailored molecular functionalities. Biomolecular electronics, lying at the borderline between physics, chemistry and biology, can be considered as a sub-field of ME. In particular, the potential applications of DNA oligomers either...

Macromolecules are the predominant physical substrate supporting information processing in organisms. Two key characteristics— conformational dynamics and self-assembly properties—render macromolecules unique in this context. Both characteristics have been investigated for technical applications. In nature’s information processors selfassembly and conformational switching commonly appear in com...

Combining biomolecular function with integrated circuit technology could usher in a new era of biologically enabled electronics. A key challenge has been coupling different molecular functions to specific chip locations for communication with the circuit. We used spatially confined electric fields to assemble different populations of DNA-coated nanowires to desired positions with an accuracy th...

This book provides, for the first time, a broad and deep treatment of the fields of both ultra low power electronics and bioelectronics. It discusses fundamental principles and circuits for ultra low power electronic design and their applications in biomedical systems. It also discusses how ultra energy-efficient cellular and neural systems in biology can inspire revolutionary low power archite...

Azurin proteins are the workhorse of protein electronics. This is a branch biomolecular electronics, recent research field which investigates electronics based on biomolecules such as proteins, peptides, amino acids, bacterial nanowires or DNA. In general, possibility including biosystems in solid-state junctions has opened way to development novel electrical devices, and have attracted enormou...

Although the term was first proposed in 1968, the birth of bioelectronics as we know it today is much more recent. In fact, the first meaning of the word bioelectronics was the intermolecular electron transfer found in biological systems [1], while its modern meaning is quite different, as discussed in this chapter. Tony Turner, founder and Editor-in-Chief of the Elsevier journal Biosensors and...