نتایج جستجو برای: biomarker panel

تعداد نتایج: 139714  

Journal: :gastroenterology and hepatology from bed to bench 0
mona zamanian –azodi mostafa rezaei –tavirani hadi hasanzadeh sara rahmatirad sona dalilan samira gilanchi

cancer has been always in a great attention in the field of molecular biology. by applying    large-scale tools such as advanced proteomics, cancer diagnosis and treatment have been improved greatly since. cancers of esophagus, gastric, and colon accounted for major health problem globally. biomarker panel could bring out the accuracy for cancer evaluation tests as it can suggest a group of can...

Journal: :Journal for ImmunoTherapy of Cancer 2015

2015
Alex Chenchik Mikhail Makhanov Leonid Iakoubov Costa Frangou

Background Several recent studies have now firmly established a link between the immune infiltrate in several human carcinoma types and prognosis and/or response to therapy. Correspondingly, increasing evidence suggests that the number, type, and location of tumor-infiltrating lymphocytes in primary tumors harbor prognostic value, and this has led to the development of a “tumor immunoscore/immu...

A. Akbari, A. Tafti, H. Zali, J. Shakeri, M. Rezaei-Tavirani, M. Samsami, M. Shahani, M.E. Akbari, N. Nafisi, S.H. Jamaldini Ezabady,

Background: Radiotherapy (RT) is recommended to all patients undergoing Breast Conserving Surgery (BCS). Two strategies can be applied to irradiation, External Beam RT (EBRT) in addition, Intraoperative Radiation Therapy (IORT). The aim of this study was to introduce a protein biomarker panel related to molecular function of IORT. Materials and Methods: Six Breast Cancer (BC) patients as a pilo...

Journal: :Brain, Behavior, and Immunity 2016
Frieder Haenisch Jason D. Cooper Andreas Reif Sarah Kittel-Schneider Johann Steiner F. Markus Leweke Matthias Rothermundt Nico J.M. van Beveren Benedicto Crespo-Facorro David W. Niebuhr David N. Cowan Natalya S. Weber Robert H. Yolken Brenda W.J.H. Penninx Sabine Bahn

BACKGROUND Bipolar disorder (BD) is a costly, devastating and life shortening mental disorder that is often misdiagnosed, especially on initial presentation. Misdiagnosis frequently results in ineffective treatment. We investigated the utility of a biomarker panel as a diagnostic test for BD. METHODS AND FINDINGS We performed a meta-analysis of eight case-control studies to define a diagnosti...

2016
Zlatan Mujagic Ettje F. Tigchelaar Alexandra Zhernakova Thomas Ludwig Javier Ramiro-Garcia Agnieszka Baranska Morris A. Swertz Ad A. M. Masclee Cisca Wijmenga Frederik J. van Schooten Agnieszka Smolinska Daisy M. A. E. Jonkers

Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fe...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Katherine R Kozak Malaika W Amneus Suzanne M Pusey Feng Su Mui N Luong Sam A Luong Srinivasa T Reddy Robin Farias-Eisner

One hundred eighty-four serum samples from patients with ovarian cancer (n = 109), patients with benign tumors (n = 19), and healthy donors (n = 56) were analyzed on strong anion-exchange surfaces using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry technology. Univariate and multivariate statistical analyses applied to protein-profiling data obtained from 140 tra...

2015
Jorn Lakowski Anai Gonzalez‐Cordero Emma L. West Ya‐Ting Han Emily Welby Arifa Naeem Samuel J. I. Blackford James W. B. Bainbridge Rachael A. Pearson Robin R. Ali Jane C. Sowden

Loss of photoreceptors due to retinal degeneration is a major cause of untreatable blindness. Cell replacement therapy, using pluripotent stem cell-derived photoreceptor cells, may be a feasible future treatment. Achieving safe and effective cell replacement is critically dependent on the stringent selection and purification of optimal cells for transplantation. Previously, we demonstrated effe...

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