it is now universally accepted that dna is the main target for damages caused by physical and chemical genotoxicants. although there are different methods to measure directly the induced dna damages but due to fast repair processes in cellular environment, most of the damages would be repaired even before sampling, therefore processed dna damages, i.e. damages left unrepaired after acting repai...

the aim of this investigation was to design and develop nanoemulsions (nes) as novel ophthalmic delivery systems for brinzolamide (bzd). phase behavior of quaternary systems composed of triacetin and capryoltm 90 (selected oils, screened through the solubility studies), various surfactants (namely, cremophor rh 40, brij 35, labrasol and tyloxapol), transcutol p (as co-surfactant) and water a...