Dr. S.-W. Hwang, J.-K. Song, Dr. X. Huang, Dr. S.-K. Kang, Dr. B. H. Kim, J.-H. Kim Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-Champaign, Urbana IL 61801 , USA H. Cheng, Prof. Y. Huang Department of Mechanical Engineering Civil and Environmental Engineering Center for Engineering and Health and Skin Disease ...

AIMS The efficacy of durable polymer drug-eluting stents (DES) is delivered at the expense of delayed healing of the stented vessel. Biodegradable polymer DES aim to avoid this shortcoming and may potentially improve long-term clinical outcomes, with benefit expected to accrue over time. We sought to compare long-term outcomes in patients treated with biodegradable polymer DES vs. durable polym...

Intimal hyperplasia appears to differ after implanting a drug-eluting stent (DES) with a biodegradable or a permanent polymer. The aim of the present study was to compare biodegradable with permanent polymer DES, since the available data are limited. One hundred patients with de novo coronary artery stenosis were included in this study. The patients were classified into 2 groups: DES with a bio...

Biodegradable polymer drug-eluting stents (DES) are innovative concepts in the era of percutaneous coronary intervention. We systematically reviewed the latest randomized evidence on the efficacy and safety of biodegradable polymer DES as compared to durable polymer DES. MEDLINE, Embase, and the Cochrane database were searched in August 2013 for eligible randomized controlled trials (RCTs) comp...

this paper discusses about preparation of biodegradable polymer /clay nanocomposites based on organically modified montmorillonite clay; i.e. cloisite 10a and biodegradable polymer chitosan by solution mixing technique and their characterization. the nanocomposites were successfully prepared and their structures were characterized by powder x-ray diffraction (xrd), particle size analyzer (beckm...

OBJECTIVE To compare the efficacy and safety of biodegradable polymer drug eluting stents with those of bare metal stents and durable polymer drug eluting stents. DESIGN Mixed treatment comparison meta-analysis of 258,544 patient years of follow-up from randomized trials. DATA SOURCES AND STUDY SELECTION PubMed, Embase, and Central were searched for randomized trials comparing any of the Fo...

Conductive biodegradable materials are of great interest for various biomedical applications, such as tissue repair and bioelectronics. They generally consist of multiple components, including biodegradable polymer/non-degradable conductive polymer/dopant, biodegradable conductive polymer/dopant or biodegradable polymer/non-degradable inorganic additives. The dopants or additives induce materia...

BACKGROUNDS Drug-eluting stents (DES) with biodegradable polymers have been developed to address the risk of thrombosis associated with first-generation DES. We aimed to determine the efficacy and safety of biodegradable polymer biolimus-eluting stents (BES) versus durable polymer DES. METHODS Systematic database searches of MEDLINE (1950 to June 2013), EMBASE (1966 to June 2013), the Cochran...

the delivery of therapeutic proteins has gained momentum with development of biotechnology. however, large molecular weight, hydrophilic nature and susceptibility to harsh environment of gastrointestinal tract (git) resulted in low absorption. the main objective of this work was the design of a particulate system for oral delivery of recombinant human growth hormone (rhgh) on the basis of parti...

Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this review, various commercially available membranes are described. Much attention is paid to the recent development of biodegradable polymers applied in GTR and GBR, and the important issues of biodegradable polymeric membranes, including their classification, latest experimental...