The discipline of Tissue Engineering has developed over the past 15–20 years as a compilation of the emerging technologies in regenerative medicine and reconstructive surgery, holding the promise of surpassing the limitations imposed by the biomaterials currently available. By utilizing the regenerative capacity of tissues it is anticipated that functional tissue analogues having the desired di...

BACKGROUND The past years have seen the development of many synthetic bone replacements. To test their biocompatibility and ability for osseointegration, osseoinduction and -conduction requires their placement within bone preferably in an animal experiment of a higher species. METHODS A suitable experimental animal model in sheep with drill holes of 8 mm diameter and 13 mm depth within the pr...

Patients treated with peritoneal dialysis (PD) are at risk for development of ultrafiltration failure and peritonitis. The relative unphysiologic composition of the currently used peritoneal dialysis fluids (PDF) is a major cause for the development of morphologic changes of the peritoneal membrane such as fibrosis and new vessel formation, ultimately resulting in ultrafiltration failure. In re...

introduction: several studies have evaluated the inflammatory reaction triggered by epiphany (eph), a contemporary endodontic sealer. however, they used conventional parameters, which need additional analysis to better understand the reactions induced by this sealer compared to other traditional sealers. methods and materials: the intensity and time span of tissue irritations for three endodont...

Irrigation solutions and intracanal medicaments are used within the root canal to clean and aid in disinfecting the dentinal walls. Although these materials are intended to be contained within the root canal, they invariably contact the periapical tissues, either through inadvertent extrusion through the apex or leaching. This paper is a review on the methodology involved in biocompatibility te...

The purpose of this investigation was to develop a coating technique and to study the characteristics of titanium–aluminum nitride [(Ti,Al)N] films deposited on a base-metal alloy (Wiron88R) substrate. Titanium–aluminum nitride thin films were deposited on the alloy surface using a reactive radiofrequency sputtering method. The electrochemical properties of three specimens with and without coat...