the aim of the present work was to assess the feasibility of accononmc8-2ep/nf as a bioadhesive material for developing controlled release gastroretentive microsponges of loratadine. modified emulsion-solvent diffusion method was employed for the preparation of microsponges (f1-f9) based on 32 factorial design. the amount of ethyl cellulose (ec) and polyvinyl alcohol (pva) were selected as inde...

Nanoparticulate systems made of biopolymers encompass promising properties as carriers and adjuvant for drug delivery. Alginate is one the most widely investigated biomaterials in field nanoparticulate delivery due to its biodegradability, biocompatibility, bioadhesivity. nanoparticles can be prepared through spray drying, ionic gelation, emulsification, covalent cross-linking, polyelectrolyte ...

The instability of implants after placement inside the body is one of the main obstacles to clinically succeed in periodontal and orthopedic applications. Adherence of fibroblasts instead of osteoblasts to implant surfaces usually results in formation of scar tissue and loss of the implant. Thus, selective bioadhesivity of osteoblasts is a desired characteristic for implant materials. In this s...

      Biodegradable nanoparticulate carriers, have important potential applications for administration of therapeutic molecules. Chitosan based nanoparticles have attracted a lot of attention upon their biological properties such as biodegradability, biocom-patibility and bioadhesivity. The aim of the present investigation was to describe the synthesis and characterization of novel biodegradabl...

biodegradable nanoparticulate carriers, have important potential applications for administration of therapeutic molecules. chitosan based nanoparticles have attracted a lot of attention upon their biological properties such as biodegradability, biocom-patibility and bioadhesivity. the aim of the present investigation was to describe the synthesis and characterization of novel biodegradable nano...

The aim of the present work was to assess the feasibility of Acconon MC8-2 EP/NF as a bioadhesive material for developing controlled release gastroretentive microsponges of loratadine. Modified emulsion-solvent diffusion method was employed for the preparation of microsponges (F1-F9) based on  32 factorial design. The amount of ethyl cellulose (EC) and polyvinyl alcohol (PVA) were selected...