نتایج جستجو برای: binding effects
تعداد نتایج: 1912460 فیلتر نتایج به سال:
با توجه به حیاتی بودن نقش آنزیم topo ii در چرخه سلولی، این آنزیم میتواند هدف درمانی مهمی در شیمی درمانی سرطان باشد. فلوروکینولون ها به عنوان مهارکننده های آنزیم توپوایزومراز (ژیراز) باکتری به خوبی شناخته شده اند و اخیرا نیز نشان داده شده است که توان مهار توپوایزومراز ii یوکاریوتیکها را هم دارند. در این راستا در این پایان نامه ترکیبات جدیدی از فلوروکینولونها به منظور مهار آنزیم توپوایزومراز انسا...
in this paper, the electronic eigenstates and energy spectra of single and two-interacting electrons confined in a concentric double quantum rings with a perpendicular magnetic field in the presence of on-center donor and acceptor impurities are calculated using the exact diagonalization method. for a single electron case, the binding energy of on-center donor and acceptor impurities ar...
recently, several studies have shown that the metal-fluoroquinolone complexes have more antibacterial and cytotoxic effects in comparison with free fluoroquinolones. these results may introduce new drugs for chemotherapy with fewer side effects. in this work a bidentated zinc (ii) complex with ofloxacin (ozc) was synthesized and cytotoxicity activities and dna binding of the resulted complex wa...
In this paper, the electronic eigenstates and energy spectra of single and two-interacting electrons confined in a concentric double quantum rings with a perpendicular magnetic field in the presence of on-center donor and acceptor impurities are calculated using the exact diagonalization method. For a single electron case, the binding energy of on-center donor and acceptor impurities ar...
In this paper, the electronic eigenstates and energy spectra of single and two-interacting electrons confined in a concentric double quantum rings with a perpendicular magnetic field in the presence of on-center donor and acceptor impurities are calculated using the exact diagonalization method. For a single electron case, the binding energy of on-center donor and acceptor impurities ar...
abstract governing was disorganized for years, when mongols attached to iran and it caused to clearing way for interference of mongols princes. dispatching of holaku to the west culminated in establishing iilkhanan government. holakus activities in destruction of abbaasis government and activities which shows his staying in iran, made force oulus juji to comparison against iilkhanis gover...
some new water-soluble schiff base complexes of na2[m(5-so3-1,2-salophen)].nh2o; (5-so3-1,2-salophen = n,n’-bis(5-sulphosalicyliden)-1,2-phenylendiamine); na2[m(5-so3-2,3-salpyr)(h2o)n].2h2o; (5-so3-2,3-salpyr = n,n’-bis(5-sulphosalicyliden)-2,3-diaminopyridine); and na2[m(5-so3-3,4-salbenz)(h2o)n].nh2o; (5-so3-3,4-salbenz = n,n’-bis(5-sulphosalicyliden)-3,4-diaminobenzophenon); where m = cu, n...
Dietary flavonoids show beneficial effects in the prevention of chronic diseases. However, flavonoid bioavailability is poor, probably due to their interaction with serum albumins. In the current work, the binding interactions of eight related flavonoids, sharing a similar core structure, with bovine serum albumin (BSA) were investigated by fluorescence spectroscopy. The binding affinities of t...
Background and Objectives: Accumulation of iron is the most common consequences of repeated blood transfusions in β-thalassemia major patients. Iron chelating effects of alpha-lipoic acid have been reported by several studies. The aim of this study was to investigate effects of supplementation with alpha-lipoic acid, as a chelator, on serum iron and hematological indices in these patients. Ma...
the binding of drugs by plasma proteins is an important phenomenon, because it influences the size of the free fraction of the drugs in plasma. in this study the influence of dipyridamole (dp) on the protein binding of propranolol (pl) and pl on the protein binding of dp were studied alone and in the presence of nicotine (nc). the equilibrium dialysis was employed for protein binding stu...
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