Neonatal jaundice occurs in nearly 70% of term and 80% of preterm babies. Management of jaundiced neonates often requires measurement of total serum bilirubin (TSB). Total serum bilirubin (TSB) is commonly determined by spectro-photometric methods by analyzing plasma or serum sample. Such techniques require drawing of blood causing pain and trauma to the neonate. In addition, there is a wide ra...

The transcutaneous bilirubinometer was evaluated in 60 term and 10 preterm infants. A significant correlation was found between the transcutaneous index and the total serum bilirubin concentration for both term and preterm infants. The reliability of the transcutaneous bilirubinometer as a screening method was confirmed, and index criteria for serum bilirubin analysis have been suggested for te...

Severe neonatal hyperbilirubinemia can be prevented by screening for neonatal jaundice. Transcutaneous bilirubin (TcB) measurement is a noninvasive method for screening neonates. The aim of this study was to examine the correlation between TcB measurement (using the JM-103 bilirubinometer) and total serum bilirubin (TSB) measurement. To our knowledge, this is the first study evaluating the usef...

BACKGROUND Neonatal jaundice is the most frequently encountered diagnostic and therapeutic problem in the newborn. In the jaundiced infant, it is thought that the binding capacity of plasma albumin is exceeded, which allows free bilirubin to diffuse into and accumulate within extravascular tissues, such as the central nervous system. Affected newborns may develop kernicterus. The standard metho...

bilirubinometer is somewhat more effective than clinical screening. If both transcutaneous index and clinical acumen were used simultaneously there would be considerably fewer false-positive screens. Discussion Previous studies evaluating the transcutaneous bilirubinometer have been carried out in Japan by Yamanouchi et al.,2 and in the USA by Hegyi et al.3 Hegyi et al.3 obtained a correlation ...

The transcutaneous (Tc) bilirubinometer was evaluated in 105 jaundiced neonates, comprising 38 Malays, 37 Chinese and 30 Indians, who had not been treated with phototherapy or exchange transfusion. Tc bilirubin index and serum bilirubin concentration correlated at statistically significant levels in all the three racial groups. Unlike the Chinese and Malay babies, the action levels, using Tc bi...

background: hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. it is a multifactorial disorder with many symptoms. generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. this review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical ap...