Introduction: Early diagnosis of biliary atresia is very important for better outcome of treatment. Ultrasonography is one of the diagnostic tools for early differentiation of  biliary atresia from other causes of neonatal cholestasis. It has been reported that triangular cord sign  (TACS) in sonography is a reliable sign for diagnosis of biliary atresia. The aim of this study was to re-assess ...

Biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. The cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described.1-3 Biliary atresia may be associated with small bowel atresia.  The surgical interventions for biliary dr...

biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. the cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described. 1-3 biliary atresia may be associated with small bowel atresia.  the surgical interventions for biliary d...

  Introduction: Early differentiation of biliary atresia from neonatal hepatitis is of utmost importance, since on time surgery of biliary atresia significantly improves the outcome. Hepatobiliary scintigraphy is an integral part of diagnosis work-up of these patients; however its specificity for diagnosis of biliary atresia is suboptimal. In this study we evaluated t...

background: biliary atresia is a 100% fatal disorder without any treatment in infants as a leading cause of cirrhosis and kasai operation, as the only operative choice, which plays a crucial role in increasing their rate of survival. nonetheless, many patients end up with liver transplantation in the future owing to various inevitable hepatic and biliary problems which do remain after the kasai...

background : most diagnostic tests for biliary atresia (ba) are invasive. this study evaluates the sensitivity and specificity of serum  tumor necrosis factor-α (tnf-α) for diagnosing extra hepatic biliary duct atresia (ehba) in infants. materials and methods : infants with cholestasis who were admitted to children′s medical center hospital were evaluated. a total of 50 infants (20 with ehba an...

background liver cirrhosis is one of the major causes of hospitalization and mortality in children. a wide spectrum of disorders including developmental abnormali­ties, infections, metabolic and genetic disorders can lead to liver cirrhosis in pediatric patients. determination of its etiology is important for treatment mo­dality, prevention of progressive liver damage, family counseling and pri...

Calreticulin plays a critical role in the etiology of multiple autoimmune diseases. It is unknown, however, whether calreticulin levels are of clinical significance for patients with biliary atresia. This study was to confirm possible correlations between serum calreticulin levels and the immunohistochemical features of biliary atresia. Serum was collected from 44 biliary atresia patients, 15 i...

introduction: early differentiation of biliary atresia from neonatal hepatitis is of utmost importance, since on time surgery of biliary atresia significantly improves the outcome. hepatobiliary scintigraphy is an integral part of diagnosis work-up of these patients; however its specificity for diagnosis of biliary atresia is suboptimal. in this study we evaluated the value of ursodeoxycholic a...

Biliary atresia, malrotation, meconium peritonitis and transient hypothyroidism are occasionally seen in neonatal infants. Biliary atresia associated with malrotation has been reported in some patients with polysplenia syndrome, but biliary atresia associated with meconium peritonitis has only been described by a few investigators. Here we present a case of meconium peritonitis due to malrotati...