Bicuspid aortic valve is traditionally considered an innocuous congenital anomaly. Due to a better and widespread availability of non-invasive imaging techniques, it has come to the fore that 30% of these cases develop complications, viz., valve abnormality (aortic regurgitation and stenosis), and aneurysm of aortic root and ascending aorta. Sinus of Valsalva aneurysm is an uncommon complicatio...

bicuspid aortic valve is traditionally considered an innocuous congenital anomaly. due to a better and widespread availability of non-invasive imaging techniques, it has come to the fore that 30% of these cases develop complications, viz., valve abnormality (aortic regurgitation and stenosis), and aneurysm of aortic root and ascending aorta. sinus of valsalva aneurysm is an uncommon complicatio...

Two dominant types of congenital bicuspid valves are described. The classical type is characterized by the presence of a low ridge or raphe along the aortic aspect of the conjoined cusp. The other is characterized by a tall raphe, the upper edge of which corresponds with the upper level of the aortic cusps. Some such ridges may result from acquired fusion of the adjacent halves of two cusps (yi...

Bicuspid aortic valve configuration and aortopathy pattern might represent different pathophysiologic sub-strates. A, Byers PH et al. The bicuspid aortic valve: an integrated phenotypic classification of leaflet morphology and aortic root shape. Association of Bicuspid aortic valve morphology and aortic root dimensions: a sub-study of the aortic stenosis progression observation measuring effect...

INTRODUCTION The cause of ascending aortic dilatation occurring in patients with congenitally bicuspid aortic valves was investigated. METHODS Flow patterns through human aortic roots with congenitally bicuspid aortic valves as well as through porcine constricted aortas were studied in a left heart simulator. Vibration was recorded as a measure of turbulence in the post-stenotic segment. Hist...

The association between ascending aortic aneurysm (AA) and bicuspid aortic valve (BAV) has been well established. Different genetic, haemodynamic and cardiovascular risk factors have been implicated in the development and progression of AA. However, to date, definite conclusions cannot be drawn regarding the exact molecular, cellular and haemodynamic mechanisms causing BAV-associated aortopathy...

BACKGROUND Transcatheter aortic valve replacement (TAVR) is being increasingly performed in patients with bicuspid aortic valve stenosis (AS). OBJECTIVES This study sought to compare the procedural and clinical outcomes in patients with bicuspid versus tricuspid AS from the Bicuspid AS TAVR multicenter registry. METHODS Outcomes of 561 patients with bicuspid AS and 4,546 patients with tricu...

tooth fracture is a common dental problem. by extension of cavity dimensions, the remaining tooth structure weakens and occlusal forces may cause tooth fracture. the aim of this study was to evaluate and compare the fracture resistance of teeth restored with direct and indirect composite restorations.sixty-five sound maxillary premolar teeth were chosen and randomly divided into five groups eac...

Isolated bicuspid pulmonary valve is a rare arterial valve anomaly with very few reports in the literature. It is usually in association with other congenital cardiac lesions. However, the true incidence of bicuspid pulmonary valve could be underestimated because of the difficulty in imaging pulmonary valve morphology with conventional two-dimensional transthoracic echocardiography. A 21-year-o...

We present a 73 years old woman who presented with pelvic cancer, ongoing sepsis and presumably a new diastolic murmur. Her transthoracic echocardiogram, as part of a sepsis screen, showed an abnormal pulmonary valve with moderate regurgitation. Trans-oesophageal echocardiography using 3D imaging showed a bicuspid pulmonary valve as the cause for the moderate regurgitation, but with no clear so...