نتایج جستجو برای: beta cells

تعداد نتایج: 1519906  

Journal: :iranian biomedical journal 0
زهرا حیدری zahra heidari مهدی هراتی mehdi harati حمیدرضا محمودزاده ثاقب hamid reza mahmoudzadeh-sagheb بیتا مودی bita moudi

background: diabetes is a major public health problem. the development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. in this study, protective effects of sodium tungstate against stz-induced beta-cell damages were investigated. methods: sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic ra...

Journal: :iranian biomedical journal 0
لیلا پیرمرادی leila pirmoradi محمدتقی محمدی mohammad taghi mohammadi اکبر صفائی akbar safaei فخرالدین مصباح fakhardin mesbah غلامعباس دهقانی gholam abbas dehghani

background: data shows vanadium protects pancreatic beta cells (bc) from diabetic animals. whether this effect is direct or through the relief of glucose toxicity is not clear. this study evaluated the potential effect of oral vanadyl sulfate (vanadium) on glycemic status and pancreatic bc of normal and diabetic rats. methods: rats were divided into five groups of normal and diabetic. diabetes ...

Journal: :hepatitis monthly 0
kai li department of molecular biology on infectious disease, second affiliated hospital, chongqing medical university, chongqing, china shijia ding department of clinical laboratory diagnostics, chongqing medical university, chongqing, china ke chen department of molecular biology on infectious disease, second affiliated hospital, chongqing medical university, chongqing, china dongdong qin department of molecular biology on infectious disease, second affiliated hospital, chongqing medical university, chongqing, china jialin qu department of molecular biology on infectious disease, second affiliated hospital, chongqing medical university, chongqing, china sen wang department of molecular biology on infectious disease, second affiliated hospital, chongqing medical university, chongqing, china

background the hepatitis b virus x (hbx) protein has long been recognized as an important transcriptional transactivator of several genes. human aldo-keto reductase family 1, member c1 (akr1c1), a member of the family of akr1cs, is significantly increased in hbx-expressed cells. objectives this study aimed to investigate the possible mechanism of hbx in regulating akr1c1 expression in hepg2.2.1...

ژورنال: Medical Laboratory Journal 2008
Abedian, S, Mirabi, A.M, Parsaee, MR,

Abstract Background and objectives: Dendritic Cells are the most important of antigen presenting cells with an effective role in immune tolerance. This study, aims to clarify the role of IFN- β in induction on dendritic cells derived by monocyte in diabetes type1 to evaluate the T cells response to beta cell specific antigenic molecule. Material and Methods: In this research, peripheral bl...

Mahnaz Mahmoudi Rad, Niki Mahmoudi Rad, Yasaman Mirdamadi,

Background: The multifunctional transforming growth factor beta (TGF-β) is a glycoprotein that exists in three isoforms. TGF-β3 expression increases in fetal wound healing and reduces fibronectin and collagen I and III deposition, and also improves the architecture of the neodermis which is a combination of blood vessels and connective tissue during wound healing. Fibroblasts are key ...

Asili, Javad , Baharara, Javad , Kerachian, Mohammad Amin , Parivar, Kazem , Soltani, Mozhgan ,

Background: Marine natural products contain a wide range of bioactive compounds with therapeutic properties that have revealed crucial properties in the treatment of some diseases. Some of these compounds have recently received considerable attention for drug discovery. In this study we examined the anti-angiogenic effect of saponin isolated from Holothuria leucospilota (sea cucumber) through e...

Background and Aim: Exercise helps in the favorable function of insulin.The obese people have metabolic complications. Thus, the present study aimed at investigating the effect of aerobic exercises on pancreas Beta- cells function in obese men. Materials and Methods: In this semi-experimental study, fasting levels of glucose, insulin, triglyceride, and pancreas beta cells function in two equal ...

امامی, سپهر , محمدصادقی, حمید, منصورآبادی, امیرحسین, موگویی, مریم, نحوی نژاد, محمدرضا,

Background: Diabetes is a metabolic disorder caused by insufficient production of insulin or insulin receptors deficiency. It is now the major cause of morbidity and hospitalization in patients with a significant financial burden to the society. The aim of this study was to evaluate the effect of Ziziphora ethanolic extract on active pancreatic beta cells on streptozotocin induced diabetic mice...

Journal: :cell journal 0

introduction: it has been shown that gama-ifn is one of the major cytokines involved in lung fibrosis. it has also been demonstrated that nitric oxide (no) may exert vasodilation, edema and cytotoxicity, and it may stimulate cytokinedependent processes in the lungs. in this study, the effect of 17-beta estradiol (17-betae2) and five alpha dihydrotestosterone (5alfa-dht) on no release by tgf bet...

A.H Magzi A.R Minagar H Naji-esfahani M Etemadifar M Saadatniya N Dana SH Haghjoy-javanmard V Homayoni

Background & Aims: Multiple sclerosis (MS) is one of the chronic autoimmune diseases of the central nervous system with unknown etiology. The present study aimed to investigate the apoptosis and nitric oxide (NO) production of endothelial cells treated with serum of patients with MS and response to interferon beta (IFN- ) therapy. Methods: Human umbilical vein endothelial cells were treated wit...

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