introduction: beta-thalassemia is the most common hereditary disease in iran. more than two million carriers of beta-thalassemia live in iran. since the iranian population is a mixture of different ethnic groups, it is necessary to determine the frequency  in the different parts of the country. materials and methods: this descriptive study is a cross sectional study with helping by professional...

Introduction: Beta-thalassemia is the most common hereditary disease in Iran. More than two million carriers of beta-thalassemia live in Iran. Since the Iranian population is a mixture of different ethnic groups, it is necessary to determine the frequency  in the different parts of the country. Materials and Methods: This descriptive study is a cross sectional study with helping by professional...

243 ! In conclusion, in countries located in the thalassemia belt, it is important to first educate the involved parties about the significance of thalassemia, then to emphasize over and over again the priority of the automated blood counts in detecting the carriers, then educate people regarding the meaning of the abnormal red cell parameters on automated blood counts. Also one has to keep in ...

alpha-Thalassemia is among the world's most common single gene disorders, which is most prevalent in the malaria belt. This geographic distribution has been attributed to a selective advantage of heterozygotes against this disease. Unexpectedly, we have found a high frequency of heterozygosity for deletional alpha-thalassemia (-alpha3.7) in Ashkenazi Jews (carrier frequency of 7.9%, allele freq...

Thalassemia minor (MT), either β or α, is the most frequent single gene mutation in human beings affecting 6% of population worldwide. It more Mediterranean region, Africa and South-East Asia. On other hand Iron deficiency anemia (IDA), nutritional secondary to gastrointestinal menstrual bleeding, cause acquired anemia. Differentiation between these two types important because both them present...

This Paper is to describe the economic burden of thalassemia as a major health problem in thalassemia belt countries like Iran. Great emphasis is placed on prenatal diagnosis to prevent the disease, as the “economic” solution from a health care policy viewpoint. The alternative method of the current screening program in Iran is outlined and discussed especially with respect to the “cost-effecti...

Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact that Bangladesh lies in the world's thalassemia belt, the information on different aspects (epid...

background: iran is one of the countries located on “the thalassemia belt” with a significant annual number of thalassemia new births. given the importance of thalassemia prevention, a program to this effect was approved in iran in 1995. screening of carrier couples and prenatal diagnosis were the two main elements of this program. in the present study, the authors have tried to address the imp...

Background: Iran is one of the countries located on “the thalassemia belt” with a significant annual number of thalassemia new births. Given the importance of thalassemia prevention, a program to this effect was approved in Iran in 1995. Screening of carrier couples and prenatal diagnosis were the two main elements of this program. In the present study, the authors have tried to address the imp...