background and purpose: progressive degeneration of dopaminergic neurons in the midbrain is the main mechanism of parkinson’s disease (pd). recent studies have shown ceftriaxone, a β-lactam antibiotic, to be a neuroprotective in various neurodegenerative disorders. hence, the present study aimed to investigate the effect of ceftriaxone on behavioral disturbances of pd in an animal model. method...

Changes in experimental animals' behavior as well as humans' behavior reflect even mild alterations in function of central nervous system. In order to detect those changes variety of tests' batteries were developed. With help of such unified tests it is possible to determine and differentiate individual behavioral parameters and establish their relation to specific CNS alterations. Behavioral t...