PURPOSE To describe a case series of postintravitreal injection, bacterial endophthalmitis heralded by hemorrhagic retinal vasculitis. METHODS Observational case series of three patients with a history of intravitreal injections for age-related macular degeneration at a tertiary referral center who presented with vision changes and eye pain that were eventually found to have bacterial endopht...

This study aimed to identify the microbial etiology of infectious endophthalmitis and to determine the antibacterial susceptibilities of bacterial isolates at an eye hospital in South China. A retrospective analysis was carried out on 330 patients with clinically diagnosed infectious endophthalmitis who underwent microbiological evaluation from January 2010 to December 2014. Of the 330 patients...

purpose: to ascertain whether the use of nested-pcr (nested polymerase chain reaction) technique leads to more rapid and accurate diagnosis of bacterial endophthalmitis. methods: the aqueous humor and vitreous samples of 24 eyes of 24 patients with bacterial endophthalmitis were evaluated by microscopy, diagnostic aerobic culture, and nested- pcr to detect the infectious agent. results: aerobic...

purpose : to assess the rate of microbial contamination of the fornix and suture needle during strabismus surgery methods : in a prospective study in khatam-al-anbia eye hospital, fornix samples and suture needles were cultured in 28 eyes of 28 patients. fornix sampling was performed before and after preparation of the eyes and the needles and remained string were transferred to culture media d...

In order to determine the effects of intraocular 0.05% povidone-iodine preparation in the prevention of bacterial endophthalmitis in a rabbit model, 28 albino rabbits were randomly assigned to 4 equal groups. A concentration of 5x 108 organisms (0.03 mL) in logarithmic growth phase of S. epidermidis, S. aureus, Proteus mirabilis and Pseudomonas aeruginosa, were injected separately in the a...

Endophthalmitis is a severe inflammation of the interior of the eye caused by the introduction of contaminating microorganisms following trauma, surgery, or hematogenous spread from a distant infection site. Despite appropriate therapeutic intervention, bacterial endophthalmitis frequently results in visual loss, if not loss of the eye itself. Although the pathogenicity of bacterial endophthalm...

Anaerobic bacterial endophthalmitis was studied in rabbits following intravitreal injection of live Fusobacterium necrophorum. Clinical response, bacterial recovery, and histopathology were studied. An inoculum of approximately 50 organisms produced endophthalmitis in 59% of injected eyes, while 1000 or more organisms produced endophthalmitis in 100% of injected eyes. The course and severity of...

We appreciate the comments by Hui et al. (3) concerning our article (1). We agree about the potential benefits of repeated intravitreal injections of antibiotics. Intravitreal antibiotics have become part of the standard treatment for endophthalmitis. The current antibiotic treatment for acute-onset bacterial endophthalmitis includes vancomycin for gram-positive coverage and either ceftazidime ...

Bacterial endophthalmitis is a serious but uncommon intraocular infection which frequently results in vision loss. Early diagnosis and appropriate therapy are associated with better visual outcome. Conventional microbiological methods are currently used for microbiological characterization of eyes with suspected endophthalmitis. However, the sensitivity of bacterial detection from aqueous and v...