Opioids are extensively used for the management of both chronic malignant and non malignant pains. One major serious limitation associated with chronic use of opioids is the development of tolerance to its analgesic effect. The effect of Bacopa monnieri, a renowned ayurvedic medicine for acquisition and expression of morphine tolerance in mice, was investigated. Bacopa monnieri, n-Butanol fract...

Rationale. Bacopa monnieri, popularly known as Brahmi, has been traditionally used in Ayurveda since ages for its memory enhancing properties. However, data on placebo-controlled trial of Bacopa monnieri on intellectual sample is scarce. Hence this study was planned to evaluate the effect of Bacopa monnieri on memory of medical students for six weeks. Objective. To evaluate the efficacy of Baco...

Bacopa monnieri L. (family Scrophulariaceae) is a traditional medicinal plant in India, commonly known as “brahmi”. Used for different diseases such asnervous disorder, respiratory problem, leprosy, splenomegaly, skin disease etc. In the present study, the ethanolic and aqueous extract of the leaf callus of Bacopa monnieri was investigated for its phytochemical analysis by modified Kirby-Bauer ...

The plant Bacopa monnieri (water hyssop, Brahmi, thyme-leaved Gratiola, herb of grace, and Indian pennywort) is a perennial, creeping herb native to the wet lands of India, particularly northeast and southern regions. Bacopa is an important plant of Ayurveda, where it is named as Brahmi, after Lord Brahma, the mythological creator of the world and originator of the science of Ayurveda. Bacopa i...

ETHNOPHARMACOLOGICAL RELEVANCE Bacopa monnieri (L.) Wettst., a plant belonging to the family Scrophulariaceae, has been used in the traditional system of Ayurvedic medicine to improve intelligence and memory for a long time. Therefore, the potential of this plant to protect against Alzheimer's disease has been raised but less supported document is available. AIM OF THE STUDY To determine the ...

The detrimental effect of neuronal cell death due to oxidative stress and mitochondrial dysfunction has been implicated in age-related cognitive decline and neurodegenerative disorders such as Alzheimer's disease. The Indian herb Bacopa monnieri is a dietary antioxidant, with animal and in vitro studies indicating several modes of action that may protect the brain against oxidative damage. In p...

s Presented 1. Amee Krishnakumar, Pretty Mary Abraham and C. S. Paulose. Enhanced 5-HT2C receptor gene expression in the cerebral cortex of pilocarpine inducedepileptic rats: Neuroprotective role of Bacopa monnieri. InternationalSymposium on Regenerative Neuroscience and Annual Meeting of Societyfor Neurochemistry (India) concurrently held at National Institute of MentalHeal...

Bacopa monnieri Linn. is an important medicinal plant belonging to family scrophulariaceae. Bacopa is a neurotonic, immuno-modulator, tranquilizing, memory and learning enhancing, cerebral activator, anti-ulcer, antispasmodic, anti-asthmatic. It is also used in Epilepsy, anxiety and depression. Major component of Bacopa are saponins Bacoside A and Bacoside B. The cell suspension culture of Baco...

Bacopa Monnieri (L) penn. Belongs to the family scrophulariaceae is commonly used in Ayurvedic system of medicine to treat various disease. The present stud examines the anti-tumous effect of ethanolic extract of whole plant bacopa monnieri (L) (EEMB) by in vitro short term chemosensitivity and in vivo tumous model test systems. EEBM dose dependently inhibited the proliferation of transformed c...

Bacopa monnieri and the constituents of this plant, especially bacosides, possess various neuropharmacological properties. Like drugs, some herbal extracts and the constituents of their extracts alter cytochrome P450 (CYP) enzymes, causing potential herb-drug interactions. The effects of Bacopa monnieri standardized extract and the bacosides from the extract on five major CYP isoforms in vitro ...