1. Rogers L. The epidemic malarial fever of Assam, or kala-azar, successfully eradicated from tea garden lines. Br Med J. 1898; 2:891–2. 2. Price JD, Rogers L. The uniform success of segregation measures in eradicating Kala-azar from Assam tea gardens: it is bearing on the probable mode of infection. BMJ. 1914;1:285–9. http://dx.doi. org/10.1136/bmj.1.2771.285 3. Kaul SM, Sharma RS, Borgohain B...

Laith Emil Azar Department of Mathematics, Al Al-Bayt University, P.O. Box. 130095, Mafraq 25113, Jordan Correspondence should be addressed to Laith Emil Azar, azar [email protected] Received 23 October 2007; Accepted 2 January 2008 Recommended by Shusen Ding By introducing some parameters we establish an extension of Hardy-Hilbert’s integral inequality and the corresponding inequality for series...

Hydroxystilbamidine or 4 : 4'-diamidino 2-hydroxy-stilbene di-jS-hydroxy-ethane sulphonate was first used by the writer for the treatment of kala-azar in 1948 and 1949 and a paper based on the results of treatment of the first six cases published (Sen Gupta, 1949). All the six cases treated had recovered and had remained free from all symptoms of kala-azar for 5, 5, 5, 4}2-, 34, and 3 months re...

6 1 Global Overview of Leishmaniasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 7 1.1 Disease Types . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 8 1.2 Disease Incidence/Distribution . . . . . . . . . . . . . . . . . ....

The preliminary results of treatment of 50 cases of kala-azar and 2 cases of post-kala-azar dermal leishmaniasis were reported by the writers (Sen Gupta and Chakravarty, 1945) last year. Of the 50 cases of kala-azar treated, two died during treatment and 48 were discharged as clinically cured. The immediate results of this trial were quite satisfactory, the immediate cure rate being about 96 pe...

In this study 4 patients were post-kala-azar dermal leishmaniasis (PKDL), whose lesions were similar to those of lepromatous and borderline leprosy, are described. In 2 patients there was no previous history of kala-azar but they were residents of an area of known endemic kala-azar. Lack of proper clinical and laboratory assessment was behind the failure to diagnose PKDL. Consequently the patie...

After two peaks of epidemic of Kala Azar, one in 1977 with 100,000 cases(l) and another in 1991-92 with 250,000 cases(2), the disease continues to be endemic in North Bihar The first line drug sodium antimony shbogluconate (SAG) used in the dosage of 20 mg/kg body weight daily for 30 days(3) or 40 days(4) has become less effective and a number of patients are unresponsive to the drug(5) Oral Fl...

the patient had visceral leishmaniasis (kala-azar), successfully treated with 30 intramuscular injections of sodium stibogluconate (SSG). Polymerase chain reaction showed Leishmania donovani DNA in a buffy coat specimen. Post-kala-azar dermal leishmaniasis (PKDL) is a chronic skin rash usually seen in apparently cured kala-azar patients in East Africa and South Asia. In the Indian subcontinent,...

Leishmania donovani in India causes visceral infection (kala-azar) and dermal infection (post-kala-azar dermal leishmaniasis). We report here the identification of polymorphism in a well-defined genetic locus among the Leishmania parasites causing the visceral and dermal manifestations, in a comparison of 15 post-kala-azar dermal leishmaniasis and 12 kala-azar patient isolates.

BACKGROUND An improved understanding in transmission variation of kala-azar is fundamental to conduct surveillance and implementing disease prevention strategies. This study investigated the spatio-temporal patterns and hotspot detection for reporting kala-azar cases in Vaishali district based on spatial statistical analysis. METHODS Epidemiological data from the study area during 2007-2011 w...