three piece bogies are widely in use by the freight railway services throughout the world. in comparison with the other freight bogies they cost less and are easier to maintain. however, they do not exhibit favorable curving behavior. amongst the methods to improve the bogie performance is the proposal to introduce lateral clearance in the bogies’ axleboxs. in the case of the three piece bogies...

Three piece bogies are widely in use by the freight railway services throughout the world. In comparison with the other freight bogies they cost less and are easier to maintain. However, they do not exhibit favorable curving behavior. Amongst the methods to improve the bogie performance is the proposal to introduce lateral clearance in the bogies’ axleboxs. In the case of the three piece bogies...

tracheomegaly or tracheobronchomegaly is a rare syndrome which is characterized by dramatic dilatation of the trachea and the major bronchi. this syndorme is usually associated with chronic respiratory infection and airway obstruction. in this paper, a case with tracheomegaly and bronchiectasis was scrutinized.

the nasal cavity possesses many advantages as a site for drug delivery, such as, ease of administration, applicability for long term treatments and a large surface area for absorption. one important limiting factor for nasal drug delivery is the limited time available for absorption within the nasal cavity due to mucociliary clearance. several drug delivery systems including different kinds of ...

In the current study, behavior of crank-slider mechanism with single and multiple clearance joints are analyzed. Using Lankarani-Nikravesh theory for estimating discontinuous contact forces in clearance joints, relevant systems have been mathematically modeled. Through numerical simulations, perturbations in response of mechanisms with clearance joints have been analyzed. Effects of increasing ...

objective(s):   recently, applications of mno2 nanoparticles and microparticles in industry, pharmacology, and medicine have considerably expanded. mn distribution and clearance from brain and spinal cord tissue compared with muscle tissue of rats after single subcutaneous injection of nanoparticles and microparticle of mno2. pain sensory threshold of rat was evaluated as neurologic consequence...

arginine vasopressin as a supplementary vasopressor in septic shock restores vascular tone and mean arterial pressure, meanwhile decreases dose and exposure time to catecholamines. the objective of this study was to evaluate the effect of vasopressin on lactate and lactate clearance as markers of tissue perfusion during septic shock. in this prospective, randomized, controlled trial, 30 patient...

objective(s) the purpose of this study was assessment of the influence of acute manic phase on the steady state pharmacokinetics of valproic acid (vpa) in bipolar patients in comparison with those of epileptic patients. materials and methods ninteen acutely manic and 25 epileptic patients who fulfilled inclusion and exclusion criteria were entered in this prospective study. blood samples were c...