the possibility that infectious agents may trigger a cascade of reactions leading to inflammation, atherogenesis and vascular thrombotic events has recently been raised. chlamydia pneumoniae is an infectious agent that has received the most attention with respect to coronary artery disease (cad). to determine the relationship between c. pneumoniae and cad, a case control study was conducted on ...

in patients requiring coronary artery bypass grafting (cabg), usually at least one of the internal mammary arteries is used. this study evaluates the degree of atherosclerotic involvement of the internal mammary artery (ima) in patients undergoing cabg. during two months period, 79 patients (66 male and 13 female with a medium age of 58 years) undergoing myocardial revascularization had a biops...

objective(s):atherosclerosis is chronic inflammatory process triggered by oxidative stress. oxidative stress can increase hydrogen peroxide (h2o2)level, which induce atherosclerosis through the processes such as formation of perivascular adipose tissue (pvat), foam cells, and atherosclerotic plaque. antioxidant is needed to control negative effects of oxidative stress. one source of antioxidant...

background: a precise understanding of the mechanism of human neointimal stenoses and atherosclerotic fibrous plaques , which give rise to thromboses in vital arteries, requires a suitable animal model that would mimic the same characteristics well. we developed a rabbit model of neointimal stenosis and fibrotic plaque rupture in the carotid artery to visualize the lesion progress and to charac...

Objective(s):Resveratrol (RES) is a polyphenol compound that has been shown a promising cardioprotective effect. However, some reports have yielded conflicting findings. Herein, we investigated the anti-atherosclerotic effects of RES in apolipoprotein E (apo E)-deficient mice on a high cholesterol diet. Materials and Methods: Firstly, atherosclerosis was induced by feeding a high cholesterol di...

objective(s):resveratrol (res) is a polyphenol compound that has been shown a promising cardioprotective effect. however, some reports have yielded conflicting findings. herein, we investigated the anti-atherosclerotic effects of res in apolipoprotein e (apo e)-deficient mice on a high cholesterol diet. materials and methods: firstly, atherosclerosis was induced by feeding a high cholesterol di...

Background and Objectives: Diabetes vascular complications are the principal cause of death in the world. Therefore, we investigated the effect of pyridoxal phosphate (PLP) on the formation of atheromatous plaque formation and renal function in the atherosclerotic rats. Materials and Methods: Male Wistar rats were randomly divided into 4 equal groups (ten rats in each group): normal, ath...

background : myocardial infarction in young age is increasing. identifying risk factors could be important for health promotion. we studied classic atherosclerotic risk factors in premature myocardial infarction. methods : in this matched case-control study, which was conducted from 2005 to 2007 in birjand county, the east of iran, atherosclerotic risk factors ( hypertension , family history of...