نتایج جستجو برای: at 1391
تعداد نتایج: 3731744 فیلتر نتایج به سال:
In the phenomenon of attentional blink, identical visual stimuli are sometimes fully perceived and sometimes not detected at all. This phenomenon thus provides an optimal situation to study the fate of stimuli not consciously perceived and the differences between conscious and nonconscious processing. We correlated behavioral visibility ratings and recordings of event-related potentials to stud...
Cytochrome P450 (P450) induction is often considered a liability in drug development. Using calibration curve–based approaches, we assessed the induction parameters R3 (a term indicating the amount of P450 induction in the liver, expressed as a ratio between 0 and 1), relative induction score, Cmax/EC50, and area under the curve (AUC)/F2 (the concentration causing 2-fold increase from baseline ...
CT7758, a carboxylate containing a4b1/a4/b7 integrin antagonist, was characterized for its pharmacokinetic profile in various in vitro and in vivo assays in support of clinical development. The oral bioavailability of CT7758 was 4% in mice, 2% in rats, 7–55% in dogs, and 0.2% in cynomolgus monkeys. The low bioavailability in rodents and monkey results from low intestinal absorption as evidenced...
[This corrects the article on p. 1391 in vol. 8, PMID: 28861022.].
[This corrects the article on p. 1391 in vol. 7, PMID: 27695430.].
http://dx.doi.org/10.1016/j.ijans.2016.09.002 2214-1391/ 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). ⇑ Corresponding author at: Department of Social and Welfare Studies, University of Linkoping, Campus Norrkoping, S-601 74 Norrköping, Sweden. E-mail address: [email protected] (K. Hjelm). F...
EMBID IRUJO, ANTONIO (Dir.), La Seguridad Hídrica. Desafíos y Contenido, Thomson Reuters Aranzadi, Cizur Menor, Navarra, 2021, 427 pp. ISBN 978-84-1391-229-5
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