conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...

During asymmetric division, a cell polarizes and differentially distributes components to its opposite ends. The subsequent division differentially segregates the two component pools to the daughters, which thereby inherit different developmental directives. In Drosophila sensory organ precursor cells, the localization of Numb protein to the cell's anterior cortex is a key patterning event and ...

During development, all cells make the decision to live or die. Although the molecular mechanisms that execute the apoptotic program are well defined, less is known about how cells decide whether to live or die. In C. elegans, this decision is linked to how cells divide asymmetrically [1, 2]. Several classes of molecules are known to regulate asymmetric cell divisions in metazoans, yet these mo...

Although little is known about how asymmetric cell division in plants is regulated, recent discoveries provide a starting point for exploring the mechanisms underlying this process. These studies reveal parallels with asymmetric division in yeast and animals, but also point to regulated cell expansion as a new mechanism of asymmetric division in plants.

A new study shows that SPEECHLESS determines cell fate in the stomatal lineage but is inherited equally by daughter cells following an asymmetric cell division. The polarity determinant BASL acts as a MAPK scaffold, targeting SPEECHLESS for degradation in the larger daughter cell.

Inductive asymmetric cell division: The WRM leads the way" (2013). This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

Recently discovered regulators of asymmetric cell division highlight differences in the mechanisms responsible for cell fate segregation in plants and animals.

We propose and demonstrate a simple method to generate ultrawideband (UWB) pulses in the optical domain using a chirped intensity modulator and an asymmetric Mach-Zehnder interferometer (AMZI). Polarity- and shape-switchable UWB Gaussian monocycle, doublet, and triplet pulses with fractional bandwidths of 158%, 134%, and 100% and center frequencies of 6.52, 9.78, and 10.1 GHz are experimentally...