microbial steroid biotransformation have found wide-reaching application for the production of more precious and functionalized compounds due to their high regio-and stereoselectivity. in this study, the possibility of using filamentous fungi aspergillus brasiliensis cells in the biotransformation of progesterone (i), a c-21 steroid hormone was studied for the first time.the fungal strain was i...

A novel species, Aspergillus brasiliensis sp. nov., is described within Aspergillus section Nigri. This species can be distinguished from other black aspergilli based on intergenic transcribed region, beta-tubulin and calmodulin gene sequences, by amplified fragment length polymorphism analysis and by extrolite profiles. A. brasiliensis isolates produced naphtho-gamma-pyrones, tensidol A and B ...

Xylanase production by a newly isolated Aspergillus niger SS7 was studied in submerged culture. The optimum initial pH for xylanase production was found to be 7.0. Different agricultural and industrial wastes were evaluated for their ability to induce xylanase production by this isolate. The best xylanase production (293.82 IU/ml) was recorded at 3% (w/v) corn cob hulls after 120 h of incubatio...

The formation of naringinase, a glycolytic enzyme produced by Aspergillus niger, is repressed by glucose. Production of the enzyme is decreased below pH 4.0 and is stimulated by the presence of substrate. Fermentation conditions are described which cause the formation of the enzyme in approximately a fivefold greater concentration than that previously described.

INTRODUCTION Human infections caused by Aspergillus brasiliensis have not yet been reported. We describe the first two known cases of fungal keratitis caused by Aspergillus brasiliensis. CASE PRESENTATIONS A 49-year-old Indian Tamil woman agricultural worker came with pain and defective vision in the right eye for one month. Meanwhile, a 35-year-old Indian Tamil woman presented with a history...

A total of 82 isolates of microfungi were isolated from 6 sandy soil samples collected from Teluk Aling beach, Pulau Pinang. The soil microfungi were isolated by using direct isolation, debris isolation and soil dilution techniques. Based on morphological characteristics, seven genera of microfungi were identified namely, Fusarium (42%), Aspergillus (24%), Trichoderma (13%), Curvularia (9%), Co...

An unspecific peroxygenase from Aspergillus brasiliensis highly expressed in Pichia pastoris catalyses aromatic hydroxylation of a number benzylic compounds.

Wild type Aspergillus niger isolates from different biotopes from all over the world were compared to each other and to the type strains of other black Aspergillus species with respect to growth and extracellular enzyme profiles. The origin of the A. niger isolate did not result in differences in growth profile with respect to monomeric or polymeric carbon sources. Differences were observed in ...

Unfolded-protein response (UPR) denotes the upregulation of endoplasmic reticulum (ER)-resident chaperone and foldase genes and numerous other genes involved in secretory functions during the accumulation of unfolded proteins into the ER. Overexpression of individual foldases and chaperones has been used in attempts to improve protein production in different production systems. We describe here...

The ethanolic extracts of aerial shoots of Mollugo cerviana and its leaf derived callus were tested for antimicrobial activity using the filter paper disk assay method. Both the extracts showed antibacterial activity against Bacillus subtilis and Escherichia Coli. The antifungal activity of the extracts against Aspergillus niger and Aspergillus flavus was nil or negligible.