OBJECTIVE One of the critical components in the postoperative care is pain. Given that little research has been done regarding the analgesic effects of intra-articular injection of ketamine, this study was aimed to compare the analgesic effect of intra-articular and extra-articular injection of morphine and ketamine compound in arthrotomy surgery under spinal anesthesia. METHODS A total of 50...

BACKGROUND AND OBJECTIVES Total knee arthroplasty (TKA) is associated with significant postoperative pain. Many intra-articular (IA) agents have been used for postoperative analgesia with inconsistent outcomes. Ketamine's enantiomer S(+), S(+)- ketamine, was recently introduced commercially, with higher analgesic potency and less side effects than the racemic form. An experimental prospective r...

Objective- Postoperative pain management in patients that undergone arthroscopy is one of the most important procedures for their rehabilitation. Analgesic injection intra-articularly can facilitate pain control in such patients. The aim of this study was to evaluate the effects of ketamine on articular cartilage in rat model. Design- Experimental study. Animals- Twenty Wistar Rats Procedure...

providing suitable analgesia following diagnostic and therapeutic arthroscopic surgeries, that areconsidered to cause some degree of postoperative pain, is a necessity in equine practice. the aim of thepresent study was to evaluate the equine synovial fluid biochemical and cytological changes as well asclinical assessments of the joint following intra-articular administration of ketamine. six a...

Providing suitable analgesia following diagnostic and therapeutic arthroscopic surgeries, that areconsidered to cause some degree of postoperative pain, is a necessity in equine practice. The aim of thepresent study was to evaluate the equine synovial fluid biochemical and cytological changes as well asclinical assessments of the joint following intra-articular administration of ketamine. Six a...

Background & Aims: One of cell- based technical issues associated with cartilage repair assay is delivering cells to the site of the parts where damage is created. Mesenchymal stem cells (MSCs) with their chondrogenic potential are ideal candidates for cartilage regeneration. High expression of cartilage hypertrophy markers by MSCs would result in apoptosis and ossification. This investigation ...

abstract   background: different methods of surgical treatment for acromioclavicular(ac) joint injury were considered in the literature. the purpose of the study was to compare intra- articular ac repair technique with the extra-articular coracoclavicular repair technique for the patients with rockwood type iii and vac joint injury when indicated.   methods: nineteen consecutive patients with r...

Arthroscopies are most commonly performed on day case basis, but postoperative pain remains a problem as more complicated procedures are performed. This study was carried out on 60 adult ASA I-II patients undergoing arthroscopic procedures. Patients were assigned into 2 equal groups; group I underwent low inflammatory surgeries, whereas group II had high inflammatory surgeries. Both groups were...

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that causes long-lasting inflammation and in the gastrointestinal tract. Depression common symptom patients with UC. (R)-ketamine new safer antidepressant than (R,S)-ketamine (S)-ketamine. Here, we examined effects of two ketamine enantiomers on dextran sulfate sodium (DSS)-induced model Ingestion 3% DSS drinking water for 14 days ...

Ketamine in subanesthetic doses became popular as a recreational drug for its strong, quickly achievable antidepressant effect and short-acting, well-tolerated psychotomimetic (hallucinogenic dissociative) effect. Numerous cases of genitourinary system dysfunction associated with ketamine use have been reported. We describe case ketamine-use-related symptoms 23-year-old man who was found to acu...