artemisinin and its derivatives are very important new class of antimalarial drugs. one of the most important artemisinin derivatives is artemether. the antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. the aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. i...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Introduction: For thousands of years, plants have been used as the main source of drug worldwide. Recently, it has been found out that the plant Artemisia annua and especially its derivatives such as artemether have anticancer properties. Methods: In this study, the anticancer effect of artemether on MCF-7 breast cancer cell line was examined. MTT assay was used to assess the viability of c...

background polyvinyl alcohol (pva) is one of the well-known polymers, which has been used in numerous biomedical applications because of its good biocompatibility. objectives due to problems made by the therapeutics already used for leishmaniasis, the aim of this study was to evaluate the effect of pva containing artemether in treating cutaneous leishmaniasis in balb/c mice. materials and metho...

Most prescribers and patients in Ghana now opt for the relatively expensive artemether/lumefantrine rather than artesunate-amodiaquine due to undesirable side effects in the treatment of uncomplicated malaria. The study sought to determine the existence of substandard and/or counterfeit artemether-lumefantrine tablets and suspension as well as artemether injection on the market in Cape Coast. S...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

conclusions artemether especially in oral treatment is an effective and simple method and may be used as a new method to treat visceral leishmaniasis. results ic50 of the drug on leishmania infantum was determined to be 25 μg/ml after 24 h. in vivo experiments indicated that oral artemether treatment of mice, during 3 days and every 6 h (0.625 mg/kg) was more significant than parenteral (0.625 ...

introduction: for thousands of years, plants have been used as the main source of drug worldwide. recently, it has been found out that the plant artemisia annua and especially its derivatives such as artemether have anticancer properties. methods: in this study, the anticancer effect of artemether on mcf-7 breast cancer cell line was examined. mtt assay was used to assess the viability of cance...

objective: leishmaniasis is one of the significant causes of morbidity and mortality in several countries. it is an important problem in endemic areas such as iran. the goal in treatment of leishmaniasis is to reduce the disease period and leave no evidence of any remaining scars or lesions. a derivative of artemisinin is artemether. scientists believe that the strong action of artemether again...