OBJECTIVE To observe the promoting effect of arnebia root oils on expression of basic fibroblast growth factor (bFGF) in skin wound of rabbits and the histomorphological changes in the wound surface, and to discuss its mechanism. METHODS Bilateral round skin wounds were made on the back of 15 rabbits. The three wounds on one side of the back of each rabbit were treated with arnebia root oils,...

The phytochemical investigation of the n-hexane extract from callus and cell suspension culture of Arnebia euchroma (Royle) Jonst. resulted in the isolation of nine isohexenylnaphthazarins: deoxyalkannin (1), alkannin (2), acetylalkannin (3), isobutyrylalkannin (4), β-hydroxyisovalerylalkannin (5), 2''-(S)-α-methylbutyrylalkannin (6), propionylalkannin (7), teracrylalkannin (8) and ac...

background wound healing is a dynamic process with inflammatory response and oxidative reaction in the damaged area. alpha ointment (ao) and arnebia euchroma (arnebia) are herbal medicines with antioxidant and anti-inflammatory effects that can be used as wound healing agents. ao is a commonly used ointment while arnebia is a newly introduced one. objectives we aimed to compare the effects of a...

antibacterial, antifungal and antioxidant activities of methanolic crude extracts from aerial parts of four arnebia species namely arnebia fimbriopetala, arnebia linearifolia, arnebia garandiflora, arnebia tubata were screened. total phenolic contents were determined by folin-ciocalteu procedure and ranged from 2.2 ± 0.13 (a. fimbriopetala) to 1.6 ± 1.0 mg (arnebia tubata) gallic acid µmol equi...

To explore uncertain aspects of the processes that maintain species boundaries, we evaluated contributions of pre- and postpollination reproductive isolation mechanisms in sympatric populations of Arnebia guttata and A. szechenyi. For this, we investigated their phylogenetic relationships, traits, microenvironments, pollinator visits, action of natural selection on floral traits, and the outcom...

BACKGROUND Burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. The present study aimed to determine the healing effect of topical treatment with Arnebia euchroma on second-degree burn wound in rats. METHODS Fifty rats were di...

BACKGROUND Wound healing is a complex process leading to regeneration of damaged skin tissue. Arnebia euchroma (AE) have many effective activities such as anti-inflammatory, antimicrobial, antioxidative, and anti-tumoral effects. The extract of AE has positive effects on burn wounds. This study is designed to investigate the healing effects of AE on excisional wounds in rats. MATERIALS AND ME...

Arnebia benthamii is a major ingredient of the commercial drug available under the name Gaozaban, which has antibacterial, antifungal, anti-inflammatory, and wound-healing properties. In the present study, in vitro antioxidant and anticancer activity of different extracts of Arnebia benthamii were investigated. Antioxidant potential of plant extracts was evaluated by means of total phenolics, D...

Objective: The present study aimed to the isolation and characterization of phytochemicals from tissue cultures of Arnebia hispidissima. The isolated compounds were evaluated for their antioxidant and antimicrobial activities. Materials and Methods: Six derivatives of alkannin and shikonin were isolated and characterized by using various physical and spectroscopic techniques from callus tissue ...