objective: asafoetida (ferula assa-foetida) is known as a valuable remedy for whooping cough, pneumonia, bronchitis in children and asthma treatment in folk medicine. in the present study the relaxant effects of the asafoetida on tracheal smooth muscle of guinea pigs and its probable mechanism(s) were examined. materials and methods: the relaxant effects of three cumulative concentrations of th...

conclusions these results showed an inhibitory effect for the extract of asafetida on muscarinic receptors of tracheal smooth muscle. results the ec50 obtained in the presence of higher concentration of the extract muscle was significantly higher compared to saline (p < 0.01). the maximum responses to methacholine in the presence of higher concentration of the extract (10 mg/ml) was significant...

The aim of the study was to evaluate the effect of crude aqueous extract of Boswellia serrata Roxb. oleo gum on urinary electrolytes, pH and diuretic activity in normal albino rats. Moreover, acute toxicity of the gum extract was assessed using mice. Albino rats were divided into five groups. Control group received normal saline (10 mg/kg), reference group received furosemide (10 mg/kg) and tes...

We report the chemopreventive activity of Acacia nilotica (Linn.) gum, flower and leaf aqueous extracts, on 7,12-dimethylbenz(a)anthracene (DMBA) induced skin papillomagenesis in male Swiss albino mice. Animals were divided into following groups: Group I (Controls) given DMBA and croton oil, with no extract ; Group II (treatment) animals treated with Acacia nilotica gum (Group II-a) (800 mg/kg ...

Objective: The purpose of this study was to investigate the protective and therapeutic effects of aqueous extract of P. atlantica gum on an experimental asthma in BALB/c mice. Materials and Methods:</stro...

Pancreas is the primary organ involved in sensing the organism’s dietary and energetic states via glucose concentration in the blood and in response to elevated blood glucose, insulin is secreted. Diabetes mellitus is a metabolic disorder which results from defects in insulin secretion. Among the various methods of Diabetes management, herbal products are best alternative drug with zero side-ef...

This present study was conducted to evaluate the hypoglycemic effect of aqueous extract of stem and bark of Coscinium fensestratum colebr in normal rats. Total 18 rats were selected and divided into the three groups each of 6 rats. G-I given 1% gum acacia, G-II given aqueous extract of C.F stem (500 mg/kg) and G-III treated with aqueous extract of C.F bark (500 mg/kg). Test drugs were given sin...

the side effects of synthetic antioxidants have been considered in different studies. accordingly, there is an increasing interest toward the use of natural substances instead of the synthetic ones. in this study, the aqueous and ethanolic extracts of pistacia vera leaves and fruits as well as hydroalcoholic extract of gum were tested for a possible antioxidant activity using in vitro methods. ...

The side effects of synthetic antioxidants have been considered in different studies. Accordingly, there is an increasing interest toward the use of natural substances instead of the synthetic ones. In this study, the aqueous and ethanolic extracts of Pistacia vera leaves and fruits as well as hydroalcoholic extract of gum were tested for a possible antioxidant activity using in vitro methods. ...

Objective: To investigate the comparative wound-healing potency of aqueous and methanol leaf extracts of Vernonia arborea Hk. Materials and Methods: Excision, incision and dead space wound models were used to evaluate the wound-healing activity of Vernonia arborea Hk., on Swiss Wistar strain rats of either sex. In excision wound model, treatment was continued till the complete healing of the wo...