The ratio of concentration of chloride in the aqueous humor compared with that in the plasma of rabbits, dogs, and human beings, was determined by the Schales and Sendroy methods. Consistent results were obtained in all the experiments by the Schales method with or without protein, and by the Sendroy method without protein. In the presence of protein, however, lower chloride concentrations were...

Ceftriaxone penetrates into the aqueous humour in man. The interaction of indomethacin on the disposition of ceftriaxone appeared to be time-dependent. Indomethacin delayed ceftriaxone penetration into, but enhanced its persistence in, the aqueous humour, permitting a period of antibioprophylaxis covering the required time for surgical treatment.

Previous work on the vitamin B12 content of the aqueous humour (Phillips, Ainley, van Peborgh, Watson-Williams, and Bottomley, I968) suggests that the levels found in a series of mainly elderly patients (mean: 299 pg./ml.) are of the same order as those found in cerebrospinal fluid (mean: 21 pg./ml.) (Kidd, Gould, and Thomas, I963). As an extension of this study, the response of aqueous vitamin...

IF it is granted that the aqueous humour is formed by the active transfer of solutes and solvent from the plasma to the aqueous, it follows that the rates of transfer of the various solvent or solute species and the steady-state composition of the aqueous will depend upon the electrochemical potential difference (P.D.) across its boundaries with the plasma. Alterations of the electrochemical P....

It has recently been shown that aqueous humor is able to obstruct flow through Nuclepore polycarbonate filters having flow dimensions similar to those found in the juxtacanalicular tissue (JCT). We undertook studies designed to identify the component(s) of aqueous humor responsible for this obstruction and to determine the mechanism of blockage. We conclude that aqueous humor contains two compo...

The penetration of rifampin into human aqueous humor was determined in 15 patients undergoing elective cataract surgery. Between 0.9 and 5.5 h after administration of a single 600-mg oral dose, concentrations ranged from 6.0 to 21.5 mg/liter in serum and from less than 0.2 to 1.3 mg/liter in aqueous humor.

Aqueous humor turnover in the cat eye determined by intracameral injection of inulin*C was found to be 2.1 per cent per minute, a value which is in close agreement with that reported for other species. The inhibition of aqueous humor formation induced by acetazolamide was dose dependent bid the quantities required were much higher than those reported necessary to lower the eye pressure. The dat...

It appears possible to utilize the inorganic phosphorus content in the aqueous humor for estimation of postmortem interval, especially if the factors relating to the body temperature are known in detail.