نتایج جستجو برای: apoptosis inducing factor
تعداد نتایج: 1012999 فیلتر نتایج به سال:
background: the anti-cancer effects of honey bee venom (bv) and chrysin might open a new window for treatment of chemo-resistant cancers. this study was designed to evaluate cytotoxic and pro-apoptotic effects of bv and chrysin on a2780cp cistplatin- resistant human ovarian cancer cells. methods: as per the study objectives, a2780cp cells were categorized to 4 groups: 3 experiment groups (treat...
in many models of programmed cell death, the mitochondrial protein aif translocates to the nucleus, where it induces the chromatin condensation and dna degradation. however, today it is well established that this flavoprotein is bifunctional. in addition to its lethal function in the nucleus of dying cells, aif plays a vital bioenergetic role in healthy ones by regulating mainly the activity of...
conclusions according to our result, 1525g/a and 1595c/t were in strong linkage disequilibrium and the polymorphisms of the trail gene in the 3’ utr region were not associated with the outcome of hbv infection. results our data showed that genotypes 1525g/a and 1595c/t were in complete linkage disequilibrium and the genotype frequencies at the two positions were the same. no significant differe...
Although the seminal paper by Kerr, Wyllie and Currie (Kerr et al., 1972), who coined the word ‘apoptosis’, stated that only nuclei but not cytoplasmic organelles would undergo major modifications in the dying cell, recent evidence suggests that no cellular compartment is spared (Ferri and Kroemer, 2001). Mitochondria are particularly affected early during the apoptotic process, and they are no...
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