Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...

malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. however, association of apocrine metaplasia in papilloma with ductal carcinoma in situ (dcis) is not very well defined. the lesions with apocrine metaplasia are not only di...

Apocrine carcinoma is a very rare form of breast malignancy with an incidence of <1% of female invasive breast carcinoma. We report a case of apocrine carcinoma in a 42-year female with marked adenosis showing apocrine metaplasia and discuss the criteria to diagnose apocrine carcinoma with the emerging concept of androgen receptor positivity with its implication on treatment and management of t...

Apocrine metaplasia is a very common finding in the female breast after the age of 25. It is so common that many people regard it as a normal component of the breast. This, however, is only really the case in apocrine sweat glands of the axilla and in the peri-areolar apocrine glands. The apocrine cell does, however, contribute to a number of different breast lesions, some of which are very tax...

Apocrine differentiation was an incidental finding in an ovarian cyst. This is considered to be a further example of Müllerian metaplasia that has not been described before and which, theoretically, could occur in any organ of Müllerian derivation (ovary, uterus, cervix or fallopian tube). It is suggested that sites of such metaplasia could in turn be the origin of primary apocrine carcinoma in...

AIM To investigate the receptor status of the sex steroid hormones in apocrine metaplasia of the breast. METHODS 82 cases of apocrine metaplasia, including 18 of the rare lesion apocrine adenosis, were studied immunohistochemically for the expression of androgen receptor, oestrogen receptor, and progesterone receptor proteins on formalin fixed, paraffin embedded tissue sections. The standard ...

Hidrocystoma is a rare cystic lesion arising from the sweat glands, and is classified into apocrine and eccrine variants, with the majority being of apocrine nature [1]. It is usually found in the head and neck region, and commonly affects the periorbital area [1, 2]. Apocrine hidrocystoma is characterized histopathologically by the presence of a unilocular or multilocular cyst situated in the ...

This case report illustrates the presence of intracystic mural nodules within the breast, a benign proliferative disorder associated with the fibrocystic spectrum: papillary apocrine metaplasia. The aim of this paper is to provide a comprehensive understanding of the physical and histological attributes of benign intracystic mural nodules, and the ability to distinguish these from a malignant p...

Monoclonal antibody B72.3 recognizing a pan-associated carcinoma antigen expressed also in metastatic human breast cancer cells has been tested using the avidin-biotin peroxidase method applied to paraffin-embedded sections in 50 samples of mammary tissue showing apocrine metaplasia and in 58 cases of other mild or severe focal epithelial proliferative changes of the breast, including mostly in...