نتایج جستجو برای: apigenin 6

تعداد نتایج: 957677  

Journal: :African journal of traditional, complementary, and alternative medicines : AJTCAM 2007
F A Hashem S A el-Sawi A A Sleem

Four apigenin glycosides were isolated from the ethyl acetate extract of the leaves of Mayodendron igneum Fam.Bignoniaceae. They were identified as apigenin 7-O-glucoside; 6-methoxy apigenin-7-O-glucoside; 6-methoxy apigenin-7-O-rhamnoglucoside and 6-hydroxy apigenin-7-O-rhamnoglucoside. In addition an isoflavone glycoside was isolated, and identified as genistin 5,4'-methyl ether. Ethanol (80%...

2015
Orsolya Farkas Orsolya Palócz Erzsébet Pászti-Gere Péter Gálfi

The in vitro anti-inflammatory effect of apigenin and its trimethylated analogue (apigenin-trimethylether) has been investigated in order to evaluate whether these flavonoids could attenuate LPS-induced inflammation in IPEC-J2 non-transformed intestinal epithelial cells. Levels of IL-6, IL-8, TNF-α, and COX-2 mRNA were measured as a marker of inflammatory response. The extracellular H2O2 level ...

2014
Xiaoxuan Zhang Guangji Wang Emily C. Gurley Huiping Zhou

BACKGROUND Apigenin is a non-toxic natural flavonoid that is abundantly present in common fruits and vegetables. It has been reported that apigenin has various beneficial health effects such as anti-inflammation and chemoprevention. Multiple studies have shown that inflammation is an important risk factor for atherosclerosis, diabetes, sepsis, various liver diseases, and other metabolic disease...

Journal: :The Journal of pharmacology and experimental therapeutics 2003
Ming Hu June Chen Huimin Lin

The purpose of this study was to determine the mechanisms responsible for intestinal disposition of apigenin in the human Caco-2 cell culture model. The results indicated that most of the absorbed apigenin (10 microM) were conjugated and only a small fraction was transported intact. The amounts of conjugates excreted, especially that of the sulfate, were dependent on days-post-seeding. Apical e...

Journal: :Annals of nutrition & metabolism 2006
Hellen Meyer Adrian Bolarinwa Guenther Wolfram Jakob Linseisen

AIM Absorption and excretion of apigenin after the ingestion of apiin-rich food, i.e. parsley, was tested. METHODS Eleven healthy subjects (5 women, 6 men) in the age range of 23-41 years and with an average body mass index of 23.9 +/- 4.1 kg/m2 took part in this study. After an apigenin- and luteolin-free diet, a single oral bolus of 2 g blanched parsley (corresponding to 65.8 +/- 15.5 micro...

Journal: :Nutrition and cancer 2006
Angela Au Boyong Li Weiqun Wang Hemant Roy Ken Koehler Diane Birt

The efficacy of dietary apigenin, a dietary flavonoid, in colon cancer prevention was investigated by evaluating the inhibition of the ornithine decarboxylase (ODC) activity and the formation of aberrant crypt foci (ACF) and by studying the ability of apigenin to block colon carcinogenesis in two mouse models. First, the activity of ODC was measured in colon cancer cells (Caco-2) and in the col...

2015
Jin-Ah Lee Sang Keun Ha EunJung Cho Inwook Choi

The aim of this study was to improve the anti-inflammatory activities of apigenin through co-treatment with resveratrol as a bioenhancer of apigenin. RAW 264.7 cells pretreated with hepatic metabolites formed by the co-metabolism of apigenin and resveratrol (ARMs) in HepG2 cells were stimulated with lipopolysaccharide (LPS). ARMs prominently inhibited (p < 0.05) the production of nitric oxide (...

Journal: :International journal of oncology 2015
Young-Ah Suh Se-Young Jo Hwa-Young Lee Chuhee Lee

Ovarian cancer is the number one cause of death from gynaecological malignancy. Platinum-based and taxol-based chemotherapy has been used as a standard therapy, but intrinsic and acquired resistance to chemotherapy is a major obstacle to treat the disease. In the present study, we found that in the chemoresistant ovarian cancer SKOV3/TR cells, interleukin-6 (IL-6), IL-6 receptor and signal tran...

2017
Young Jin Jang Hyo Jeong Son Yong Min Choi Jiyun Ahn Chang Hwa Jung Tae Youl Ha

Apigenin, a natural flavone abundant in various plant-derived foods including parsley and celery, has been shown to prevent inflammation and inflammatory diseases. However, the effect of apigenin on skeletal muscle hypertrophy and myogenic differentiation has not previously been elucidated. Here, we investigated the effects of apigenin on quadricep muscle weight and running distance using C57BL...

2016
Su-Mi Cha Jeong-Dan Cha

Although a broad range of biological and pharmacological activities of apigenin have been reported, the mechanism(s) behind its antibacterial effects are not fully understood. In this study, we investigated the synergistic antibacterial activity of apigenin in combination with existing antimicrobial agents against oral bacteria. The combination effect of apigenin was evaluated against oral bact...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید