abstract   backgrounds: pott's disease is a rare form of extrapulmonary tuberculosis, and presents with several clinical patterns. delay in diagnosis and management may cause serious complications. we conducted a retrospective study between 1991- 2006 to evaluate clinical presentation, radiologic and laboratory findings, and therapeutic approaches to spinal tuberculosis.   methods: we reviewed ...

abstract   backgrounds: pott's disease is a rare form of extrapulmonary tuberculosis, and   presents with several clinical patterns. delay in diagnosis and management may   cause serious complications. we conducted a retrospective study between 1991-   2006 to evaluate clinical presentation, radiologic and laboratory findings, and therapeutic   approaches to spinal tuberculosis.   methods:...

This report describes a rare case of a patient with splenic tuberculosis (TB) who developed spontaneous splenic rupture after 10 weeks of antituberculous chemotherapy. The patient responded well to the antituberculous regimen prior to the spontaneous splenic rupture. We considered a paradoxical reaction as a cause of the splenic rupture. The patient underwent splenectomy and continuously receiv...

Tuberculosis of parotid lymph nodes is a rare condition. Although uncommon, it must be included in differential diagnosis of a discrete parotid gland swelling or mass. Early recognition of the disease entity and awareness of its potential existence can spare the patient unnecessary surgical intervention. A 13-year-old female patient presented with a painless swelling in left preauricular region...

BACKGROUND Fluoroquinolone is recommended as a pivotal antituberculous agent for treating multi-drug-resistant pulmonary tuberculosis. However, its effectiveness as first-line treatment remains controversial. The present study was conducted to validate the fluoroquinolone-containing regimen for drug-sensitive pulmonary tuberculosis. METHODS We searched MEDLINE, EMBASE, and the Cochrane Centra...

BACKGROUND/AIMS We investigated the time of onset of antituberculous drug-induced hepatotoxicity (ADIH) and related characteristics. METHODS Adult patients (n = 1,031) treated with first-line antituberculous drugs between February 2009 and January 2013 were enrolled. RESULTS Of the 1,031 patients, 108 patients (10.5%) developed ADIH a mean of 39.6 ± 43.7 days after treatment initiation. Twe...

Isoniazid (INH) is the mainstay of management against Mycobacterium tuberculosis. INH-induced acute pancreatitis is an uncommon association and with dearth of literature on it. We are reporting a case of an 11 years old girl who developed acute pancreatitis after 2 weeks of antituberculous therapy. An INH free regimen was started. She was discharged and followed without complications.

of tuberculosis disappeared with no evidence of recurrence at 1-year follow-up. Drug interactions between Rif and protease inhibitors have prompted clinical studies of HIV-infected patients that have documented the efficacy of Rib as a substitute for Rif in the 6-month antituberculous regimen [2–4]. Intolerance to Rif is not rare and could be another indication for Rib. The tolerance profile of...

A case of claustrophobia in a 45-year old male tuberculous in-patient receiving antituberculous drug is reported. The patient presented with the clinical features of claustrophobia after eighteen months of therapy. Isoniazid was, probably, the most likely cause since. The symptoms recurred on reintroduction of INH containing regimens. There was no recurrence of symptoms on resumption of non-Iso...