Malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. Because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. Traditional medicine is one of the important sources of new antiplasmodial drugs.In this study, twenty methanolic extracts from different parts of sixteen medicinal plants used i...

malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. traditional medicine is one of the important sources of new antiplasmodial drugs.in this study, twenty methanolic extracts from different parts of sixteen medicinal plants used i...

Malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. Because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. Traditional medicine is one of the important sources of new antiplasmodial drugs.In this study, twenty methanolic extracts from different parts of sixteen medicinal plants used i...

OBJECTIVE To evaluate the in vivo antiplasmodial activity of the ethanol leaf extract of Stachytarpheta cayennensis in the treatment of various ailment in Niger Delta region of Nigeria, in Plasmodium berghei infected mice. MATERIALS AND METHODS The ethanolic leaf extract of Stachytarpheta cayennensis (90-270 mg/kg/day) was screened for blood schizonticidal activity against chloroquine sensiti...

some dorema species are used in persian traditional medicine. in the present study the total extract from the roots of dorema hyrcanum koso-pol. was investigated for its in vitro (pldh assay) and in vivo (peters’ 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line mdbk (mtt test). the ic50 values for a chloroquine- sensitive (3d7) and a chl...

Malaria remains o n e o f the leading causes of morbidity and mortality in tropical countries, and the alarming spread of the drugs resistant malaria parasite underscores the need to develop new antimalarial compounds. In this study, the phytochemical constituents, in vivo antiplasmodial, and cytotoxic activity of methanolic extracts of Achyranthes aspera and Ficus thoningii were evaluated usin...

Background & Aim: Antiplasmodial activity of leaf extract of Breynia nivosa was evaluated to ascertain the folkloric claim of its antimalarial activity. Experimental: The crude leaf extract (75 – 225 mg/kg), of Breynia nivosa was investigated for antiplasmodial activity against chloroquine sensitive Plasmodium berghei infections in mice. The antiplasmodial activity d...

Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in vitro (pLDH assay) and in vivo (Peters’ 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line MDBK (MTT test). The IC50 values for a chloroquine- sensitive (3D7) and a chl...

The study aimed to evaluate the in vivo antiplasmodial activity of an aqueous extract aerial parts Ipomoea pes-caprea mice infected with Plasmodium berghei. Extracts were obtained from decoction dried leafy stem plant. extracts used for evaluation which was done according two methods: Rane test curative effect while Peters suppressive effect. Four concentrations (25, 50, 100 and 200 mg/kg) admi...

background & aim: antiplasmodial activity of leaf extract of breynia nivosa was evaluated to ascertain the folkloric claim of its antimalarial activity. experimental: the crude leaf extract (75 – 225 mg/kg), of breynia nivosa was investigated for antiplasmodial activity against chloroquine sensitive plasmodium berghei infections in mice. the antiplasmodial activity during early and establis...