the etiopathogenesis of dementia in alzheimer's disease (ad) is still unclear. however, long-term oxidative stress is believed to be one of the major contributing factors in progression of neuronal degeneration and decline of cognitive function in ad. in order to assess the presence of oxidative stress in ad, we examined the enzymatic activities of the erythrocyte cu-zn superoxide dismutase (cu...

background: there are studies that indicated dyshomeostasis of oxidant/antioxidant and trace elements in breast cancer patients, but the data regarding the status of these parameters in various stages of breast cancer are limited. the aim of this study was to highlight the status of these biochemical factors in various stages of breast cancer. methods: fifty-eight breast cancers patients partic...

abstract background and objective: diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. we aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (tos) and total antioxidant (tas) status in the cardiac tissue of diabetic rats. material and methods: fourty-two male wistar rats with an average wei...

cyfluthrinm[cyano[4-fluoro-3-phenoxyphenyl]-methyl-3-[2,2-dichloroethenyl]-2,2-dimethyl-cyclo propane carboxylate] is a synthetic pyrethroid insecticide, that has both contact and stomach poison action. the present study evaluated the long-term toxic effects of cyfluthrin on antioxidant status in buffalo calves. oral administration of cyfluthrin at a dose rate of 10 and 20 mg/kg/d for 11 consec...

this study was conducted to investigate the effect of different levels of savory (satureja hortensis) powder and its essential oil on performance and antioxidant status of broiler chickens under heat stress (34±2 ˚c for 8 hours per day). a total of 336 one-day-old male broiler chicks (ross-308) were divided into 6 treatments and 4 replications (14 birds per replicate). experimental diets were a...

six hundred 1-d-old male broilers (ross 308) were assigned to four experimental groups; each was composed of 5 floor pen replications of 30 birds including control (no enalapril), 15, 30 and 60 ppm enalapril in the drinking water. from d 21 to 49, all the chicks were exposed to low ambient temperature to induce ascites. mortalities were inspected to determine the cause of death and diagnose of ...

this study aimed to investigate the potency of silymarin (smn) and melatonin (mel) on restoring the pancreatic  cells in streptozotocin (stz)-induced diabetic rats. male wistar rats were divided into five groups, including: control (c), untreated diabetic (d), smn-treated diabetic (50 mg/kg, orally), mel-treated diabetic (10 mg/kg, i.p.), and smn plus mel-treated diabetic rats. diabetes was in...

this study was conducted to investigate the effects of dietary influence of aspirin on growth performance, antioxidant status and mortality in the broilers subjected to cold-induced ascites. a total six hundred 1-d old male broilers (ross, 308) were randomly allotted to four treatment groups, with five replicate pens per treatment and 30 birds each. the experimental groups were kept in a cold c...

in this study, the essential oil (eo) of pistacia atlantica subsp. kurdica was added at the rate of 10 g/kg of daily diet of rainbow trout and its effect on gut microbiota (enterobacteriaceae, lactobacillus spp., total count), growth performance and antioxidant status of rainbow trout fillet was investigated. sixty apparently healthy rainbow trout with an approximate weight of 150 g ±3.5 were r...

mycophenolate mofetil (mmf) as an immunosuppressive agent is used to prevent graft rejection. one of the adverse effects of long time administration of mmf is the gastrointestinal disorder. this study aimed to investigate the gastroprotective effect of silymarin (smn) on mmf-induced gastrointestinal (gi) disorders. twenty-four adult female wistar rats were assigned into three groups including t...