the objective of the present investigation was to assess the possible involvement ofgabaergic mechanism in analgesic effect of aqueous extract of origanum vulgare (org)in a rat model of acute pain test. sixty-three anaesthetized male wistar rats (200-250 g) werecannulated into the left ventricle. five to seven days after the recovery from surgery, org extractwas intraventricularly injected at d...

Water, methanol and ethanol extracts of Evodia rutaecarpa were tested for antinociceptive activity, which were correlated with the contents of evodiamine, rutaecarpine and evodine. Determination of contents was achieved by chromatographic techniques. Extracts were evaluated for antinociceptive activities using hot-plate test; acetic acid-induced writhing test and formalin test. All three extrac...

This study examined the antinociceptive and antiinflammatory activities of the stem bark of the traditional medicinal plant, Hildegardia poulifolia (Sterculiaceae), an endangered species. Methanolic bark extract of this species was investigated for the antinociceptive effect by using acetic acid-induced writhing and hot plate methods in albino mice and antiinflammatory activity by carrageenan, ...

OBJECTIVE The present study was carried out to investigate the antinociceptive and anti-inflammatory activities of virgin coconut oil (VCO) produced by the Malaysian Agriculture Research and Development Institute (MARDI) using various in vivo models. MATERIALS AND METHODS Two types of VCOs, produced via standard drying (VCOA) and fermentation (VCOB) processes were used in this study. Both VCO...

pistacia vera l., a member of anacardiaceae family, has been used for sedation and analgesia in traditional medicine. in this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of p. vera leaves were investigated in mice. the antinociceptive activity was studied using hot plate and writhing tests. the effect of the extracts a...

Evaluation of anti-inflammatory and antinociceptive activities of untreated mung bean (MB), germinated mung bean (GMB), and fermented mung bean (FMB) was performed on both in vitro (inhibition of inflammatory mediator, nitric oxide(NO)) and in vivo (inhibition of ear oedema and reduction of response to pain stimulus) studies. Results showed that both GMB and FMB aqueous extract exhibited potent...

Pistacia vera L., a member of Anacardiaceae family, has been used for sedation and analgesia in traditional medicine. In this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of P. vera leaves were investigated in mice. The antinociceptive activity was studied using hot plate and writhing tests. The effect of the extracts a...