diet can play a vital role in cancer prevention. nowadays the scientists are looking for food materials which can potentially prevent the cancer occurrence. the purpose of this research is to examine anti-mutagenic and apoptotic effects of apigenin in human lymphoma cells. in present study human chronic lymphocytic leukemia (eheb cell line) were cultured in rpmi 1640 (sigma), supplemented with ...

Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...

peperomia pellucida leaf extract was characterized for its anticancer, antimicrobial, antioxidant activities, and chemical compositions. anticancer activity of p. pellucida leaf extract was determined through colorimetric mtt (tetrazolium) assay against human breast adenocarcinoma (mcf-7) cell line and the antimicrobial property of the plant extract was revealed by using two-fold broth micro-di...

Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. the effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different university hospitals in shiraz (iran) and in a group of 18 unexposed nurses as control group. the cytogenetic repercussions of exposure were asses...

This guideline provides clinicians caring for children with an approach to assessing the acute emetogenic potential of antineoplastic therapies. It was developed by an international, inter-professional panel of clinicians and researchers using AGREE and CAN-ADAPTE methods. The emetogenicity of antineoplastic agents was evaluated and ranked as high, moderate, low, or minimal. The emetogenicity o...

The aims of the present study were to clarify the work environment contamination by antineoplastic drugs in a hospital ward and to assess the genotoxic risks to nurses who routinely handle antineoplastic drugs in Japan. The exposed group consisted of 19 female nurses who routinely handled antineoplastic drugs. The control group consisted of 18 female nurses who did not handle antineoplastic dru...