on the basis of preliminary in vitro screening tests, a competent strain of pantoea agglomerans ena1 (p. agg. ena1) recovered from soybean nodule was evaluated for its antagonistic activity against macrophomina phaseolina causal agent of charcoal rot of soybean. the results of various in vitro assays showed that p. agg. ena1 is capable of exerting strong antagonistic effect against m. phaseolin...

BACKGROUND & OBJECTIVE Dermatophytes responsible for causing dermatophytoses in humans have acquired resistance to certain antimycotic drugs. We isolated naturally occurring actinomycetes with an ability to produce metabolites having antimycotic property. The timecourse of antifungal metabolite production in terms of arbitrary units (AU) under optimum conditions was studied. METHODS Water and...

This study was performed to investigate the antifungal substances and the antifungal activity against fungi of lactic acid bacteria (LAB) isolated from kimchi. LAB from kimchi in Imsil showed antifungal activity against Penicillium brevicompactum strain FI02. LAB LI031 was identified as Lactobacillus sakei subsp. Antifungal substances contained in L. sakei subsp. ALI033 culture media were unsta...

The study of metabolites from a new strain of Aspergillus tamarii evolved from our interest in fungi as a source of biologically active compounds. An interesting spectrum of antifungal activity exhibited by broth cultures of this organism led to the isolation of a metabolite, A30641, showing in vitro activity against fungi and Gram-positive bacteria. In addition to this new substance, a previou...

In the aim of searching for new antifungal products from marine origin, we have isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa using bio-guided (antifungal) HPLC methods. The molecular structure of this compound was elucidated by spectrometric techniques IR, UV, MS and NMR. The isolated metabolite show...

The structure of the antifungal metabolite coniothyriomycin was systematically modified by changing the acids of the open chain imide, modification of the hydrophobicity, variation in the degree of saturation, replacement of carbons by nitrogen or oxygen, and incorporation of the open chain molecule into cyclic arrangements. Structure-activity studies showed that antifungal activity was retaine...