the major objective in endodontic therapy is to disinfect the entire root canal system. this requires that the pulpal content be eliminated as sources of infection. this goal may be accomplished by mechanical instrumentation and chemical irrigation, in conjunction with medication of the root canal between treatment sessions. microorganisms and their by-products are considered to be the major ca...

background: lactic acid bacteria (lab) isolated originally from sourdough are probably the best candidates as biopreservatives, because they are well adapted to the non-aseptic conditions in sourdough fermentation. the aim of the present study was to study antifungal properties of a dominant endogenous lab isolated from whole barley sourdough. methods: whole barley flour from a mixture of barle...

conclusions our work suggested that pomegranate (punica granatum l.) peel has potential antifungal activity against candidiasis, and it is an attractive option for the development of new management strategies for candidiasis. results maximum inhibitions were attributed to peel extract of the pomegranate cultivar against candida species. the greatest antifungal inhibition among the eight differe...

background and purpose: candida species constitute an important group of opportunistic fungi, which cause various clinical diseases. considering the resistance of some candida species to conventional antifungal agents, treatment of such cases may be challenging and complicated. the purpose of this study was to evaluate and compare the antifungal activities of euphorbia macroclada latex and fluc...

background: with increasing use of antibiotics, the number and type of microbial resistance to antibiotics have been raised and at result the need for synthesis of new antimicrobials or acquire new sources of antimicrobial is indisputable. in this study the antimicrobial effects of the flowering aerial parts of glaucium vitellinum and gaillonia aucheri were investigated. m aterials and methods:...

background and purpose: actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. invasive aspergillosis (ia) due to aspergillus fumigatus has been identified as individual drug-resistant aspergillus spp. to be an emerging pathogen opportunities a global scale. this paper described the antifungal activity of one terrestrial actinomycete against the...

background: the rise of opportunistic fungal infections highlights the need for development of new antimicrobial agents. antimicrobial peptides (amps) and antifungal peptides (afps) are among the agents with minimal resistance being developed against them, therefore they can be used as structural templates for design of new antimicrobial agents. methods: in the present study four antifungal pep...

a major group of drugs that have been approved for the therapy of systemic fungal infections are polyene antibiotics. amphotericin b (amb), one of the polyene antibiotics, has been used to treat serious systemic fungal infections by binding to sterols such as ergosterol in fungal cells membrane, and is believed to form pores in the membrane and create a transmembrane ion-channel. since all euka...

background and purpose: chronic granulomatous disease (cgd) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (nadph) oxidase complex. this disorder results in recurrent life-threatening bacterial and fungal infections. aspergillus species are the most common fungal infections in these patients. case report: herein, we present a case of fungal infection in a girl with ...