several previous studies of adults have reported that the amplitudes of the sural and superficial radial nerve (sn and srn) action potentials are larger with antidromic than with orthodromic recordings. however, this difference has not been documented in children. this study evaluated the amplitudes of sn and srn sensory nerve action potentials (snaps), obtained with antidromic and orthodromic ...

Contrary to orthodromic spikes that are generated in sensory organs and conveyed to CNS, antidromic spikes are generated in the axon terminals of the sensory neurons within the CNS and are conveyed to the peripheral sensory organ. Antidromic discharges are observed in primary afferent neurons of both vertebrates and invertebrates and seem to be related to the rhythmic activity of central neural...

In the rat hippocampal formation, degeneration of CA4-derived afferent fibers provokes the growth of mossy fiber collaterals into the fascia dentata. These aberrant fibers subsequently form granule cell-granule cell synapses. The hippocampal slice preparation was employed to determine whether these recurrent connections are electrophysiologically functional. Hippocampal slices were prepared 12 ...

The electric organs of Astroscopus are modified from extraocular muscles and innervated by the enlarged oculomotor nuclei. The electromotor neuron somata are contacted by fine processes with which they form gap junctions. Presynaptic vesicles and active zones are also present, although physiological data give no indication of chemically mediated transmission. Antidromic stimulation produces lon...

Latencies of orthodromic and antidromic sensory potentials were compared in 16 normal median nerves. Peak latency was longer in the antidromic sensory response in every case. The peak latency of the antidromic sensory response depended on the distance between the recording electrodes; with shorter interelectrode distances it was similar to that of orthodromic sensory response.

Although sensory nerves in vitro are known to convey both orthodromic (sensory) and antidromic (putatively modulating) action potentials, in most cases very little is known about their bidirectional characteristics in intact animals. Here, we have investigated both the sensory coding properties and antidromic discharges that occur during real walking in the freely behaving crayfish. The activit...