aim: the increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. who recommends did (daily defined dose/ 100 inhabitant /day) as a standard tool for measurement of antibiotic consumption. since there was not any information regarding the antibiotics usage pattern in the north of iran, the aim of this study was determine this in our centre.method: this cr...

Mitochondria are dynamic intracellular organelles involved in many vital cellular functions. It is important to maintain good mitochondrial biogenesis and health. Mitochondrial dysfunction is known to be associated with many neurodegenerative diseases, such as, Parkinson’s, Alzheimer’s and amyotrophic lateral sclerosis. In the 1930’s Warburg described a link between mitochondrial function and t...

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

We demonstrate here the presence of a distinct mature CD4+8- T cell subset in mouse thymus. This subset, termed "Thy0," is delineated by the absence of 3G11 expression from about half of the 6C10-/HSAlow/- fraction of CD4+8- thymic cells. Thy0 is detectable from the neonatal period and largely contributes the Th0-type diverse cytokine production previously reported for the HSAlow/-CD4+ thymic p...

The DJH structure is of particular importance for diversity in the immunoglobulin heavy chain because it encodes most of CDR3. Here, we investigate mechanisms responsible for generating the DJH structure. We found DFL16.1 was used at a high frequency in normal and transformed pre-B cells (fetal liver > 50%, A-MuLV lines approximately equal to 25%). One DFL16.1JH1 structure was found repeatedly ...