Naturally occurring coumarins possess antibacterial and antifungal properties. In this study, these natural and synthetic coumarins were used to evaluate their antifungal activities against Aspergillus flavus, which produces aflatoxins. In addition to control antifungal activities, antiaflatoxigenic properties were also determined using a high-performance liquid chromatography in conjunction wi...

Lactobacillus casei KC-324 was tested for its ability to inhibit aflatoxin production and mycelial growth of Aspergillus flavus ATCC 15517 in liquid culture. Aflatoxin B1 biosynthesis and mycelial growth were inhibited in both simultaneous culture and individual antagonism assays,suggesting that the inhibitory activity was due to extracellular metabolites produced in cell-free supernatant fluid...

The antifungal and antiaflatoxigenic effects of two series of coumarinyl thiosemicarbazides on Aspergillus flavus NRRL 3251 were studied. Fungi were grown in YES medium for 72 h at 29 °C in the presence of 0, 0.1, 1, and 10 μg mL-1 of coumarinyl thiosemicarbazides: one series with substitution in position 7 and another with substitution in position 4 of the coumarin core. Dry mycelia weight det...

Twelve methylenedioxy-containing compounds including piperine and 10 piperine-like synthetic compounds were assessed to determine their antifungal and antiaflatoxigenic activities against Aspergillus flavus ATCC 22546 in terms of their structure-activity relationships. Piperonal and 1,3-benzodioxole had inhibitory effects against A. flavus mycelial growth and aflatoxin B₁ production up to a con...

the inhibitory activities of aqueous and solvent extracts of twelve selected medicinal plants were evaluated against biosynthesis of aflatoxin b1 (afb1) by aspergillus flavus. the a. flavus was isolated from maize, and aflatoxin b1 biosynthesis was confirmed by comparison with standard afb1 using tlc method. in vivo antiaflatoxigenic efficacies of activity guided solvent extracts were determine...

In the present study the mould incidence, ergosterol and aflatoxin B1 (AFB1) contaminations were evaluated in different food based seed samples viz., chickpea, cowpea, green gram, groundnut, Indian bean, maize, sorghum, soya bean and sunflower collected from different agro-climatic regions of Karnataka (India). The agar plate and standard blotter methods were employed for determination of the f...

This study was performed to investigate effect of essential oils on Aspergillus spore germination, growth, and mycotoxin production. In vitro antifungal and antiaflatoxigenic activities of Cymbopogon martinii, Foeniculum vulgare, and Trachyspermum ammi essential oils were carried out on toxigenic strains of Aspergillus species. Plant materials were hydrodistilled for 4-5 h in Clevenger apparatu...

Plants are unique sources of useful metabolites. Plant essential oils display a wide range of antimicrobial effects against various pathogens. Here, we studied the essential oil from the seeds of Carum copticum. We monitored aflatoxin by high-performance liquid chromatography. Results show that Carum copticum essential oil inhibits Asergillus parasiticus growth and prevents aflatoxin production...