Anti-tuberculosis medications can cause various side effects, including drug rash. When a patient on anti-tuberculosis treatment (ATT) develops rash, we usually stop all medicines, rechallenge the patient with medications individually, and find the offending agent. It should be mentioned that drug rash can be also a manifestation of other diseases. Herein, we report a case of tuberculosis who d...

Oculogyric crisis (OGC), frequently caused by medications such as antiemetics, antidepressants, and anti-epileptics, is an acute dystonic reaction of the ocular muscles. It consists of wide-staring gaze (lasting variably from seconds to minutes), seizures, and a widely-opened mouth. To date, there have been no reports of anti-tuberculosis medications such as rifampicin, isoniazid, pyrazinamide ...

Abdominal tuberculosis (TB) is generally responsive to medical treatment, and early diagnosis and management can prevent unnecessary surgical intervention. However, intravenous therapy is needed for severe forms of tuberculosis with extensive gastrointestinal involvement. The authors report an immunocompetent patient with gastrointestinal TB who was successfully managed with a combination of su...

a 35-year-old lady presented with a history of decreased vision in her right eye from one week before her referral. she did not report any significant systemic disease. ocular findings were compatible with the diagnosis of central retinal vein occlusion. systemic laboratory tests were all within normal limits except for mantoux test (ppd) which was positive, 18 mm induration and 2+ redness. che...

introduction tuberculosis of the foot is an unusual type of skeletal tuberculosis. case presentation we report on an eighty-six-year-old woman, who presented pain and purulent discharge from the right foot for 10 months. the final diagnosis was confirmed with a culture of mycobacterium tuberculosis. discussion diagnosis of this form of tuberculosis is established with some delay due to the unco...

Background. Individual sensitivity to isoniazid in tuberculosis patients is determined by the presence of N-acetyltransferase 2 (NAT2) enzyme gene allelic variants genome. Evaluation quantitative and qualitative alterations peripheral blood can be used for diagnosis, disease severity estimation, or as a clue estimation anti-tuberculosis chemotherapy effectiveness safety. Aim: Find associations ...

background: human immunodeficiency virus (hiv) makes infected cases prone to opportunistic infections like tuberculosis (tb) due to impaired immunity of the body, especially multi drug resistant (mdr) ones which are a major concern. with hiv outbreak starting late in the 20th century, the international health community is observing a huge rise in the incidence of this complex disease. herein, w...

Granulomatous inflammation in the lung may occur from a variety of causes. Many of these are the result of specific antigens that reach the lung and induce a granulomatous response. A prototype of this schema is pulmonary tuberculosis where the organism serves as the inciting antigen. Treatment of tuberculosis is aimed at killing and clearing the organism. It would be foolhardy and potentially ...

silicosis is considered to be among the occupational lung diseases and associated with sandblasting, mining, quarrying and tunneling. acute silicosis is usually progressive diseaseand despite treatment with corticosteroids it leads to cardio-respiratory failure and death. alveolar silicoproteinosis is one of it’s acute presentations due to exposure to silica dust and lungs filling with proteina...