نتایج جستجو برای: anti rejection therapy
تعداد نتایج: 996561 فیلتر نتایج به سال:
background: thymoglobuline (tg), is used for both induction and rejection therapy in kidney transplantation (tx). this study was conducted to compare between adding tg or not to the conventional drugs to evaluate the rate of rejections, infections and costs. methods: in two groups of patients, each of 45 cases group a received conventional drugs (cyclosporine, mycophenolate and prednisolone) an...
Background: The goal of Induction therapy is to prevent acute rejection during the early posttransplantation period by providing a high degree of Immunosuppression at the time of transplantation. Induction therapy is often considered essential to optimize outcomes, especially in patients at high risk for poor short-term outcomes. The optimal prophylactic induction immunosuppressive therapy to p...
introduction: due to its immunosuppressive properties, local graft irradiation (lgi) has been proposed as a second line therapy for treatment of acute kidney rejection. case presentation: in this case-series we report 6 patients with biopsy proven acute kidney allograft rejection refractory to conventional antirejection therapy who underwent lgi for treatment of acute rejection at our center. t...
studies have shown that patients who do not produce donor specific and / or panel reactive anti-hla antibodies have a longer graft survival. the purpose of this study was to evaluate the posttransplant humoral immune response towards hla-class i antigens and the measurement of the serum creatinine levels which are used in monitoring posttransplant function of kidney. serum samples from 132 rena...
BACKGROUND Acute kidney allograft rejection is a major cause for declining graft function and has a negative impact on the long-term graft survival. The majority (90%) of acute rejections are T-cell mediated and, therefore, the anti-rejection therapy targets T-cell-mediated mechanisms of the rejection process. However, there is increasing evidence that intragraft B-cells are also important in t...
The immune changes that accompany pregnancy are in several ways similar to those required for solid organ transplantation. Successful pregnancy involves controlled downregulation of the maternal immune system with increased tolerance of foetal cells expressing paternal HLA antigens. This is mediated principally by human chorionic gonadotrophin which has a documented ability to alter the action ...
INTRODUCTION Due to its immunosuppressive properties, local graft irradiation (LGI) has been proposed as a second line therapy for treatment of acute kidney rejection. CASE PRESENTATION In this case-series we report 6 patients with biopsy proven acute kidney allograft rejection refractory to conventional antirejection therapy who underwent LGI for treatment of acute rejection at our center. T...
BK virus-associated nephropathy (BKVAN) is one of the major causes of allograft dysfunction in kidney transplant (KT) patients. We compared BKVAN combined with acute rejection (BKVAN/AR) with BKVAN alone in KT patients. We retrospectively analyzed biopsy-proven BKVAN in KT patients from 2000 to 2011 at Seoul National University Hospital. Among 414 biopsies from 951 patients, biopsy-proven BKVAN...
Despite recent improvements in immunosuppressive therapy, hepatic allograft rejection remains a major cause of morbidity and late graft loss in patients undergoing liver transplantation. Although some biochemical tests suggest hepatic allograft damage, the gold standard for defining rejection remains based on morphologic findings. Acute cellular rejection usually occurs within the first 3 weeks...
Allograft rejection is a significant cause of renal transplant failure which needs prompt diagnosis and treatment for graft salvage. Angiotensin II type 1 receptor antibody-mediated (AT1R-AMR) increasingly being identified as the etiology in kidney recipients with allograft but without detectable human leukocyte antigen (HLA) antibodies. While some reports have suggested that AT1R-AMR may be re...
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