seaweeds have caused an emerging interest in the biomedical area, mainly due to their contents of bioactive substances which show great potential as anti-inflammatory, anti-microbial, anti-viral and anti-tumoral drugs. despite the diversity in quality and quantity of the mediterranean tunisian coast flora, with its large contains of marine organisms and seaweeds, most of them have not yet been ...

Abstract Nature has been a wellspring of therapeutic operators for a huge number of years and an exceptional number of present day drugs have been secluded from common sources. Higher plants, as wellsprings of restorative mixes, have kept on assuming a prevailing part in the support of human wellbeing since old circumstances. More than half of all cutting edge clinical medications are of...

a new series of transition metal complexes of co(ii), ni(ii), cu(ii) and zn(ii), has beensynthesized from the knoevenagel condensate schiff base ligand(l) derived from β-ketoanilideand furfural with o-phenylenediamine and diethylmalonate. structural features were determinedby spectral and analytical techniques. square-planar geometry has been adopted by thecomplexes except cobalt complex which ...

objective(s) aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. in the present study different extracts of roots of a. indica were evaluated for their anti­inflammatory, antipruritic and mast cell stabilizing activity. materials and methods anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...

leptadenia reticulata was reported to be used for several medicinal purposes. the present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of l. reticulata. the anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. pro inflammatory mediators (il2, il6, tnf-α) in serum of treated and control organism ...

the methanolic extract of whole plants of solanum nigrum l. was investigated for anti-inflammatory activity on the experimental animal models. the methanolic extract at a concentration of 100 mg.kg-1 and 200 mg.kg-1, p.o. showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. anti-inflammatory activity of the tested extract...

methanolic extract of solanum trilobatum linn. (mest) belonging to the family of solanacea was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its anti-inflammatory activity by subjecting into carrageenan, and cotton pellet induced granuloma tests for its effect on acute and chronic phase inflammation models in...

there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...

chalcone (1,3-diarylprop-2-en-1-one) derivatives have been introduced as selective cyclooxygenase-2 inhibitors. in the present study, anti-nociceptive and anti-inflammatory effects of eight novel compounds were evaluated in male mice and wistar rats by using the writhing and formalin-induced paw edema tests respectively. the activities of the compounds were compared with celecoxib as a referenc...

fenugreek (trigonella foeum-graecum l.) has been used in iranian traditional medicine for treatment of different kinds of inflammation disorders. in the present study, anti- inflammatory activity of the methanolic extract of the plant (at doses of 100, 200 and 400 mg/kg) were studied using carrageenan-induced edema method and compared with the effects of dexamethasone and ibuprofen. various con...